Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 2280133..2280679 Replicon chromosome
Accession NZ_CP061080
Organism Mesirhizobium sp. NIBR3 strain N3

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag IAI54_RS10580 Protein ID WP_187972301.1
Coordinates 2280425..2280679 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag IAI54_RS10575 Protein ID WP_187972300.1
Coordinates 2280133..2280438 (-) Length 102 a.a.

Genomic Context

IAI54_RS10570IAI54_RS10600IAI54_RS10605IAI54_RS10610IAI54_RS10615IAI54_RS10555IAI54_RS10560IAI54_RS10565IAI54_RS10575IAI54_RS10580IAI54_RS10585IAI54_RS10590IAI54_RS10595IAI54_RS10620
Location: 2278902..2280014 (1113 bp)
Type: Others
Protein ID: WP_187972299.1
Location: 2282501..2282959 (459 bp)
Type: Others
Protein ID: WP_187972305.1
Location: 2283024..2283590 (567 bp)
Type: Others
Protein ID: WP_187972306.1
Location: 2283690..2283947 (258 bp)
Type: Others
Protein ID: WP_187972307.1
Location: 2283948..2284349 (402 bp)
Type: Others
Protein ID: WP_187972308.1
Location: 2276171..2276731 (561 bp)
Type: Others
Protein ID: WP_187973110.1
Location: 2277075..2278172 (1098 bp)
Type: Others
Protein ID: WP_187972297.1
Location: 2278293..2278754 (462 bp)
Type: Others
Protein ID: WP_187972298.1
Location: 2280133..2280438 (306 bp)
Type: Antitoxin
Protein ID: WP_187972300.1
Location: 2280425..2280679 (255 bp)
Type: Toxin
Protein ID: WP_187972301.1
Location: 2280734..2280997 (264 bp)
Type: Others
Protein ID: WP_187972302.1
Location: 2281019..2281312 (294 bp)
Type: Others
Protein ID: WP_187972303.1
Location: 2281379..2282392 (1014 bp)
Type: Others
Protein ID: WP_187972304.1
Location: 2284353..2285387 (1035 bp)
Type: Others
Protein ID: WP_187972309.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IAI54_RS105552276171..2276731-561WP_187973110.1TRAP transporter small permease-
IAI54_RS105602277075..2278172-1098WP_187972297.1TRAP transporter substrate-binding protein-
IAI54_RS105652278293..2278754-462WP_187972298.1Lrp/AsnC family transcriptional regulator-
IAI54_RS105702278902..2280014+1113WP_187972299.14-hydroxyphenylpyruvate dioxygenase-
IAI54_RS105752280133..2280438-306WP_187972300.1BrnA antitoxin family proteinAntitoxin
IAI54_RS105802280425..2280679-255WP_187972301.1BrnT family toxinToxin
IAI54_RS105852280734..2280997-264WP_187972302.1hypothetical protein-
IAI54_RS105902281019..2281312-294WP_187972303.1hypothetical protein-
IAI54_RS105952281379..2282392-1014WP_187972304.1fumarylacetoacetate hydrolase family protein-
IAI54_RS106002282501..2282959+459WP_187972305.1MarR family transcriptional regulator-
IAI54_RS106052283024..2283590+567WP_187972306.1lipocalin family protein-
IAI54_RS106102283690..2283947+258WP_187972307.1type II toxin-antitoxin system prevent-host-death family antitoxin-
IAI54_RS106152283948..2284349+402WP_187972308.1type II toxin-antitoxin system VapC family toxin-
IAI54_RS106202284353..2285387-1035WP_187972309.1L-threonine 3-dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(26-97)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9384.79 Da        Isoelectric Point: 7.0112

>T172032 WP_187972301.1 NZ_CP061080:c2280679-2280425 [Mesirhizobium sp. NIBR3]
MRILWDEPKRLANIDKHGLDFSALTEDFFASAVIRVARGERYLAVGELSSFFVAVVFRPLGAEALSVISMRPANRKETPP
YDAS

Download         Length: 255 bp

>T172032 NZ_CP079156:167930-168400 [Klebsiella pneumoniae subsp. pneumoniae]
GTGATCTTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
CTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACCCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATACAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAATTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11454.84 Da        Isoelectric Point: 8.6343

>AT172032 WP_187972300.1 NZ_CP061080:c2280438-2280133 [Mesirhizobium sp. NIBR3]
MTPRKLQAEFKPGRGYSREDWDAVSDNPEWTEEDFARARPFADVFPELAASIRRGRPPVENPKKQVTLRLDADVVERFRA
GGPGWQSRMNEALRKAAGLAD

Download         Length: 306 bp

>AT172032 NZ_CP079156:167490-167933 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAAAACTTTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
TGTAGCGCTCCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGTGAACCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCAACCACATTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTTATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAGGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAAACGGGAGCCTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References