Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 551177..551783 Replicon chromosome
Accession NZ_CP061080
Organism Mesirhizobium sp. NIBR3 strain N3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag IAI54_RS02545 Protein ID WP_187970862.1
Coordinates 551475..551783 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag IAI54_RS02540 Protein ID WP_187970861.1
Coordinates 551177..551482 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAI54_RS02510 547001..547921 + 921 WP_187972987.1 TerC family protein -
IAI54_RS02515 548235..549032 + 798 WP_187970857.1 sel1 repeat family protein -
IAI54_RS02520 549098..549394 - 297 WP_187970858.1 hypothetical protein -
IAI54_RS02525 549551..549859 + 309 Protein_485 type II toxin-antitoxin system RelE/ParE family toxin -
IAI54_RS02530 549852..550157 + 306 WP_187970859.1 putative addiction module antidote protein -
IAI54_RS02535 550268..551056 - 789 WP_187970860.1 exodeoxyribonuclease III -
IAI54_RS02540 551177..551482 - 306 WP_187970861.1 putative addiction module antidote protein Antitoxin
IAI54_RS02545 551475..551783 - 309 WP_187970862.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IAI54_RS02550 551926..553335 - 1410 WP_187970863.1 type I glutamate--ammonia ligase -
IAI54_RS02555 553385..553723 - 339 WP_187970864.1 P-II family nitrogen regulator -
IAI54_RS02560 554029..555549 + 1521 WP_187970865.1 NAD(P)H-hydrate dehydratase -
IAI54_RS02565 555645..556637 + 993 WP_187970866.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-83)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11442.94 Da        Isoelectric Point: 10.7140

>T172029 WP_187970862.1 NZ_CP061080:c551783-551475 [Mesirhizobium sp. NIBR3]
MLDLKQTETFRKWWMRLGDERARGVIFSRLDRLAYGHVGDVRPVGDGVSELRIHHGPGYRVYFQRRGDTIVVLLCGGDKS
TQARGTSGPRSALRRNGASEDG

Download         Length: 309 bp

>T172029 NZ_CP079155:3557455-3557772 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGCCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10724.20 Da        Isoelectric Point: 5.6882

>AT172029 WP_187970861.1 NZ_CP061080:c551482-551177 [Mesirhizobium sp. NIBR3]
MAEKLTTFDPAEGLTSNEAAAAFMAEAFASEDAGYIAHALGVVARATGMTRIARETGLSREQLYRSFSADGNPTLKTTLL
VMKALGIELTARSPAHRPEPL

Download         Length: 306 bp

>AT172029 NZ_CP079155:3557765-3558052 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCAACGGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References