Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 137335..138188 Replicon chromosome
Accession NZ_CP061080
Organism Mesirhizobium sp. NIBR3 strain N3

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag IAI54_RS00645 Protein ID WP_187970545.1
Coordinates 137652..138188 (+) Length 179 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag IAI54_RS00640 Protein ID WP_187970544.1
Coordinates 137335..137664 (+) Length 110 a.a.

Genomic Context

IAI54_RS00605IAI54_RS00610IAI54_RS00615IAI54_RS00620IAI54_RS00625IAI54_RS00630IAI54_RS00635IAI54_RS00640IAI54_RS00645IAI54_RS00660IAI54_RS00665IAI54_RS00650IAI54_RS00655
Location: 132934..133359 (426 bp)
Type: Others
Protein ID: WP_187972952.1
Location: 133477..134280 (804 bp)
Type: Others
Protein ID: WP_187970538.1
Location: 134308..134829 (522 bp)
Type: Others
Protein ID: WP_187970539.1
Location: 134987..136270 (1284 bp)
Type: Others
Protein ID: WP_187970540.1
Location: 136275..136619 (345 bp)
Type: Others
Protein ID: WP_187970541.1
Location: 136644..136880 (237 bp)
Type: Others
Protein ID: WP_187970542.1
Location: 136861..137133 (273 bp)
Type: Others
Protein ID: WP_187970543.1
Location: 137335..137664 (330 bp)
Type: Antitoxin
Protein ID: WP_187970544.1
Location: 137652..138188 (537 bp)
Type: Toxin
Protein ID: WP_187970545.1
Location: 140493..141596 (1104 bp)
Type: Others
Protein ID: WP_187970547.1
Location: 141736..142368 (633 bp)
Type: Others
Protein ID: WP_187970548.1
Location: 138210..139445 (1236 bp)
Type: Others
Protein ID: WP_187970546.1
Location: 139565..140374 (810 bp)
Type: Others
Protein ID: WP_210321194.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IAI54_RS00605132934..133359+426WP_187972952.1VOC family protein-
IAI54_RS00610133477..134280+804WP_187970538.1hypothetical protein-
IAI54_RS00615134308..134829+522WP_187970539.1CoA-binding protein-
IAI54_RS00620134987..136270+1284WP_187970540.1O-acetylhomoserine aminocarboxypropyltransferase-
IAI54_RS00625136275..136619+345WP_187970541.1cupin domain-containing protein-
IAI54_RS00630136644..136880+237WP_187970542.1DUF4160 domain-containing protein-
IAI54_RS00635136861..137133+273WP_187970543.1DUF2442 domain-containing protein-
IAI54_RS00640137335..137664+330WP_187970544.1DUF1778 domain-containing proteinAntitoxin
IAI54_RS00645137652..138188+537WP_187970545.1GNAT family N-acetyltransferaseToxin
IAI54_RS00650138210..139445-1236WP_187970546.1cytochrome P450-
IAI54_RS00655139565..140374-810WP_210321194.1class D beta-lactamase-
IAI54_RS00660140493..141596+1104WP_187970547.1FAD-dependent oxidoreductase-
IAI54_RS00665141736..142368+633WP_187970548.1ATP-dependent Clp protease proteolytic subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(49-151)

Antitoxin

Vibrio phage ICP1, Orf50

(28-104)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 19200.75 Da        Isoelectric Point: 6.8486

>T172028 WP_187970545.1 NZ_CP061080:137652-138188 [Mesirhizobium sp. NIBR3]
MAEIGEASRGGENGLSAPVPLTADHDPSEFDCGEPALNDWLRHRALKNESRFSRTYVVCEGNRVVGYFCILAGAVERGAA
PSRVRRNAPDTIPVSVIGRLAVDKAHAGKGLGTDILSDALRRIALASRSIGIGAVLVHAKDDAARRFYRRCAEFIEYPDD
SRTLFLPIETVVAALSPD

Download         Length: 537 bp

>T172028 NZ_CP079155:c3433289-3433071 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12235.08 Da        Isoelectric Point: 9.9842

>AT172028 WP_187970544.1 NZ_CP061080:137335-137664 [Mesirhizobium sp. NIBR3]
MTRVPSPRSPVLDDVAVAERSTETKGSINLRIEANTRQLIDDAAAVLGKTRTEFMVETARREAIDVLLDQRLFVLDPERY
GAFMHALDNPPAPGPKLRSLLRRVPAWQK

Download         Length: 330 bp

>AT172028 NZ_CP079155:c3433690-3433316 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References