Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 202616..203132 Replicon chromosome
Accession NZ_CP061079
Organism Pseudomonas chlororaphis strain qlu-1

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag HLB40_RS00855 Protein ID WP_009041601.1
Coordinates 202851..203132 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag HLB40_RS00850 Protein ID WP_009046356.1
Coordinates 202616..202861 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HLB40_RS00825 198384..199379 + 996 WP_101281621.1 sulfotransferase family protein -
HLB40_RS00830 199345..200103 - 759 WP_009046352.1 slipin family protein -
HLB40_RS00835 200105..201490 - 1386 WP_009046353.1 nodulation protein NfeD -
HLB40_RS00840 201714..202175 + 462 WP_016705004.1 YbaK/EbsC family protein -
HLB40_RS00845 202306..202551 + 246 WP_009046355.1 DUF2789 domain-containing protein -
HLB40_RS00850 202616..202861 + 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HLB40_RS00855 202851..203132 + 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HLB40_RS00860 203265..203693 + 429 WP_028681511.1 winged helix DNA-binding protein -
HLB40_RS00865 203690..205774 + 2085 WP_101281622.1 FUSC family protein -
HLB40_RS00870 205771..205980 + 210 WP_007932080.1 DUF1656 domain-containing protein -
HLB40_RS00875 205977..206873 + 897 WP_101281623.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T172021 WP_009041601.1 NZ_CP061079:202851-203132 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

>T172021 NZ_CP079155:c99103-99001 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT172021 WP_009046356.1 NZ_CP061079:202616-202861 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp

>AT172021 NZ_CP079155:98994-99139 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References