Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1203454..1203599 Replicon chromosome
Accession NZ_CP061062
Organism Klebsiella pneumoniae strain HKP0018

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1203490..1203592 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1203454..1203599 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBX29_RS05620 1198584..1200644 + 2061 WP_004151449.1 oligopeptidase B -
IBX29_RS05625 1200648..1201307 - 660 WP_002911407.1 exodeoxyribonuclease X -
IBX29_RS05630 1201386..1201616 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IBX29_RS05635 1201729..1202103 + 375 WP_039819395.1 CopC domain-containing protein YobA -
IBX29_RS05640 1202107..1202976 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
IBX29_RS05645 1202993..1203331 + 339 WP_002911404.1 YebY family protein -
- 1203454..1203599 - 146 - - Antitoxin
- 1203490..1203592 + 103 - - Toxin
IBX29_RS05650 1203968..1204111 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
IBX29_RS05655 1204216..1205184 - 969 WP_014907334.1 VirK/YbjX family protein -
IBX29_RS05660 1205341..1205994 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
IBX29_RS05665 1205991..1206182 - 192 WP_002911395.1 YebW family protein -
IBX29_RS05670 1206280..1206519 - 240 WP_002911393.1 YebV family protein -
IBX29_RS05675 1206635..1208068 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T171992 NZ_CP061062:1203490-1203592 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT171992 NZ_CP061062:c1203599-1203454 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References