Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2056184..2056329 Replicon chromosome
Accession NZ_CP061053
Organism Klebsiella pneumoniae strain HKP0067

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2056220..2056322 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2056184..2056329 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBX31_RS09925 2051314..2053374 + 2061 WP_004151449.1 oligopeptidase B -
IBX31_RS09930 2053378..2054037 - 660 WP_002911407.1 exodeoxyribonuclease X -
IBX31_RS09935 2054116..2054346 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IBX31_RS09940 2054459..2054833 + 375 WP_039819395.1 CopC domain-containing protein YobA -
IBX31_RS09945 2054837..2055706 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
IBX31_RS09950 2055723..2056061 + 339 WP_002911404.1 YebY family protein -
- 2056184..2056329 - 146 - - Antitoxin
- 2056220..2056322 + 103 - - Toxin
IBX31_RS09955 2056698..2056841 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
IBX31_RS09960 2056946..2057914 - 969 WP_014907334.1 VirK/YbjX family protein -
IBX31_RS09965 2058071..2058724 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
IBX31_RS09970 2058721..2058912 - 192 WP_002911395.1 YebW family protein -
IBX31_RS09975 2059010..2059249 - 240 WP_002911393.1 YebV family protein -
IBX31_RS09980 2059365..2060798 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T171976 NZ_CP061053:2056220-2056322 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT171976 NZ_CP061053:c2056329-2056184 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References