Detailed information of TA system TA171934

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 5983607..5984148
• Replicon: chromosome
• Accession: NZ_CP061008
• Organism: Achromobacter xylosoxidans strain GD03

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IAG39_RS27785
• Protein ID: WP_118932564.1
• Coordinates: 5983873..5984148 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IAG39_RS27780
• Protein ID: WP_118932565.1
• Coordinates: 5983607..5983873 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IAG39_RS27755	5979285..5980070	+	786	WP_013391441.1	enoyl-ACP reductase FabI	-
IAG39_RS27760	5980119..5980517	-	399	WP_059372921.1	OsmC family protein	-
IAG39_RS27765	5980707..5981387	+	681	WP_059372919.1	tellurite resistance TerB family protein	-
IAG39_RS27770	5981410..5982396	-	987	WP_118932566.1	tripartite tricarboxylate transporter substrate binding protein	-
IAG39_RS27775	5982475..5983359	-	885	WP_059372915.1	carboxylating nicotinate-nucleotide diphosphorylase	-
IAG39_RS27780	5983607..5983873	+	267	WP_118932565.1	ribbon-helix-helix domain-containing protein	Antitoxin
IAG39_RS27785	5983873..5984148	+	276	WP_118932564.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IAG39_RS27790	5984193..5985122	-	930	WP_118932595.1	hypothetical protein	-
IAG39_RS27795	5985322..5985549	+	228	WP_059372911.1	hypothetical protein	-
IAG39_RS27800	5985601..5986506	-	906	WP_118932563.1	LysR family transcriptional regulator	-
IAG39_RS27805	5986648..5987637	+	990	WP_059372906.1	tripartite tricarboxylate transporter substrate binding protein	-
IAG39_RS27810	5987701..5988981	+	1281	WP_118932562.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (10-45)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10634.34 Da
• Isoelectric Point: 10.3397

>T171934 WP_118932564.1 NZ_CP061008:5983873-5984148 [Achromobacter xylosoxidans]
MTLKWTSKALSDLVRLYEFLAPVNKSAATRAVQALAKAPTILQTNPRIGEQLFQFEPREVRRILVGEYEIRYEIQDAVVH
VLRLWHTRESR

Nucleotide

• Length: 276 bp

>T171934 NZ_CP079099:485294-485644 [Bacillus velezensis]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9773.14 Da
• Isoelectric Point: 4.7914

>AT171934 WP_118932565.1 NZ_CP061008:5983607-5983873 [Achromobacter xylosoxidans]
MTAATKVLTTHVPLPLADKVDQMATRLERSRGWIMKQALSAWIAQEEERDRLTQEALADVDAGRVVDHLAVQAWAESLGT
DEPLPVPR

Nucleotide

• Length: 267 bp

>AT171934 NZ_CP079099:485007-485288 [Bacillus velezensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA