Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2043469..2043740 Replicon chromosome
Accession NZ_CP060974
Organism Escherichia coli strain EC4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2043599..2043702 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2043469..2043740 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9192_RS09830 2040024..2040686 - 663 WP_000944256.1 exodeoxyribonuclease X -
H9192_RS09835 2040710..2041366 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
H9192_RS09840 2041468..2041698 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H9192_RS09845 2041837..2042211 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H9192_RS09850 2042215..2043087 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H9192_RS09855 2043100..2043441 + 342 WP_000976476.1 YebY family protein -
- 2043469..2043740 - 272 - - Antitoxin
- 2043599..2043702 + 104 - - Toxin
H9192_RS09860 2043837..2044493 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H9192_RS09865 2044494..2044685 - 192 WP_000457842.1 YebW family protein -
H9192_RS09870 2044790..2045026 - 237 WP_001295499.1 YebV family protein -
H9192_RS09875 2045144..2046583 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171824 NZ_CP060974:2043599-2043702 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171824 NZ_CP060974:c2043740-2043469 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References