Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2055006..2055277 Replicon chromosome
Accession NZ_CP060969
Organism Escherichia coli strain EC5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2055136..2055239 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2055006..2055277 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9193_RS09945 2051561..2052223 - 663 WP_000944256.1 exodeoxyribonuclease X -
H9193_RS09950 2052247..2052903 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
H9193_RS09955 2053005..2053235 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H9193_RS09960 2053374..2053748 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H9193_RS09965 2053752..2054624 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
H9193_RS09970 2054637..2054978 + 342 WP_000976472.1 YebY family protein -
- 2055006..2055277 - 272 - - Antitoxin
- 2055136..2055239 + 104 - - Toxin
H9193_RS09975 2055374..2056030 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
H9193_RS09980 2056031..2056222 - 192 WP_001296140.1 YebW family protein -
H9193_RS09985 2056327..2056563 - 237 WP_001295499.1 YebV family protein -
H9193_RS09990 2056681..2058120 - 1440 WP_061344305.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1982284..2071892 89608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171786 NZ_CP060969:2055136-2055239 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171786 NZ_CP060969:c2055277-2055006 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References