Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4676827..4677098 Replicon chromosome
Accession NZ_CP060950
Organism Escherichia coli strain EC9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4676865..4676968 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4676827..4677098 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9196_RS22470 4673984..4675423 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H9196_RS22475 4675541..4675777 + 237 WP_001295499.1 YebV family protein -
H9196_RS22480 4675882..4676073 + 192 WP_001296140.1 YebW family protein -
H9196_RS22485 4676074..4676730 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 4676827..4677098 + 272 - - Antitoxin
- 4676865..4676968 - 104 - - Toxin
H9196_RS22490 4677126..4677467 - 342 WP_000976472.1 YebY family protein -
H9196_RS22495 4677480..4678352 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H9196_RS22500 4678356..4678730 - 375 WP_000204700.1 CopC domain-containing protein YobA -
H9196_RS22505 4678869..4679099 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H9196_RS22510 4679201..4679857 + 657 WP_241407744.1 carbon-nitrogen hydrolase family protein YobB -
H9196_RS22515 4679881..4680543 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171700 NZ_CP060950:c4676968-4676865 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171700 NZ_CP060950:4676827-4677098 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References