Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 951864..952135 Replicon chromosome
Accession NZ_CP060946
Organism Escherichia coli O157:H7 str. EC10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 951902..952005 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 951864..952135 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9197_RS04610 949021..950460 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H9197_RS04615 950578..950814 + 237 WP_001295499.1 YebV family protein -
H9197_RS04620 950919..951110 + 192 WP_001296140.1 YebW family protein -
H9197_RS04625 951111..951767 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 951864..952135 + 272 - - Antitoxin
- 951902..952005 - 104 - - Toxin
H9197_RS04630 952163..952504 - 342 WP_000976472.1 YebY family protein -
H9197_RS04635 952517..953389 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H9197_RS04640 953393..953767 - 375 WP_000204700.1 CopC domain-containing protein YobA -
H9197_RS04645 953906..954136 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H9197_RS04650 954238..954894 + 657 WP_241407744.1 carbon-nitrogen hydrolase family protein YobB -
H9197_RS04655 954918..955580 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171651 NZ_CP060946:c952005-951902 [Escherichia coli O157:H7 str. EC10]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171651 NZ_CP060946:951864-952135 [Escherichia coli O157:H7 str. EC10]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References