Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2058001..2058272 Replicon chromosome
Accession NZ_CP060924
Organism Escherichia coli strain EC14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2058131..2058234 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2058001..2058272 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9201_RS09855 2054556..2055218 - 663 WP_000944256.1 exodeoxyribonuclease X -
H9201_RS09860 2055242..2055898 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
H9201_RS09865 2056000..2056230 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H9201_RS09870 2056369..2056743 + 375 WP_000204699.1 CopC domain-containing protein YobA -
H9201_RS09875 2056747..2057619 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
H9201_RS09880 2057632..2057973 + 342 WP_000976492.1 YebY family protein -
- 2058001..2058272 - 272 - - Antitoxin
- 2058131..2058234 + 104 - - Toxin
H9201_RS09885 2058369..2059025 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
H9201_RS09890 2059026..2059217 - 192 WP_001296140.1 YebW family protein -
H9201_RS09895 2059322..2059558 - 237 WP_001295499.1 YebV family protein -
H9201_RS09900 2059676..2061115 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171530 NZ_CP060924:2058131-2058234 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171530 NZ_CP060924:c2058272-2058001 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References