Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1963821..1964092 Replicon chromosome
Accession NZ_CP060899
Organism Escherichia coli strain EC21

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1963951..1964054 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1963821..1964092 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9206_RS09505 1960376..1961038 - 663 WP_000944256.1 exodeoxyribonuclease X -
H9206_RS09510 1961062..1961718 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
H9206_RS09515 1961820..1962050 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H9206_RS09520 1962189..1962563 + 375 WP_000204699.1 CopC domain-containing protein YobA -
H9206_RS09525 1962567..1963439 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
H9206_RS09530 1963452..1963793 + 342 WP_000976492.1 YebY family protein -
- 1963821..1964092 - 272 - - Antitoxin
- 1963951..1964054 + 104 - - Toxin
H9206_RS09535 1964189..1964845 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
H9206_RS09540 1964846..1965037 - 192 WP_001296140.1 YebW family protein -
H9206_RS09545 1965142..1965378 - 237 WP_001295499.1 YebV family protein -
H9206_RS09550 1965496..1966935 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171379 NZ_CP060899:1963951-1964054 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171379 NZ_CP060899:c1964092-1963821 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References