Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2067215..2067486 Replicon chromosome
Accession NZ_CP060892
Organism Escherichia coli strain EC22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2067345..2067448 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2067215..2067486 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9207_RS09955 2063770..2064432 - 663 WP_000944256.1 exodeoxyribonuclease X -
H9207_RS09960 2064456..2065112 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
H9207_RS09965 2065214..2065444 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H9207_RS09970 2065583..2065957 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H9207_RS09975 2065961..2066833 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H9207_RS09980 2066846..2067187 + 342 WP_000976476.1 YebY family protein -
- 2067215..2067486 - 272 - - Antitoxin
- 2067345..2067448 + 104 - - Toxin
H9207_RS09985 2067583..2068239 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H9207_RS09990 2068240..2068431 - 192 WP_000457842.1 YebW family protein -
H9207_RS09995 2068536..2068772 - 237 WP_001295499.1 YebV family protein -
H9207_RS10000 2068890..2070329 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171354 NZ_CP060892:2067345-2067448 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171354 NZ_CP060892:c2067486-2067215 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References