Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2047813..2048084 Replicon chromosome
Accession NZ_CP060880
Organism Escherichia coli strain EC26

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2047943..2048046 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2047813..2048084 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9209_RS09900 2044368..2045030 - 663 WP_000944256.1 exodeoxyribonuclease X -
H9209_RS09905 2045054..2045710 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
H9209_RS09910 2045812..2046042 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H9209_RS09915 2046181..2046555 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H9209_RS09920 2046559..2047431 + 873 WP_039268383.1 copper homeostasis membrane protein CopD -
H9209_RS09925 2047444..2047785 + 342 WP_000976476.1 YebY family protein -
- 2047813..2048084 - 272 - - Antitoxin
- 2047943..2048046 + 104 - - Toxin
H9209_RS09930 2048181..2048837 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H9209_RS09935 2048838..2049029 - 192 WP_000457842.1 YebW family protein -
H9209_RS09940 2049134..2049370 - 237 WP_001295499.1 YebV family protein -
H9209_RS09945 2049488..2050927 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171295 NZ_CP060880:2047943-2048046 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171295 NZ_CP060880:c2048084-2047813 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References