Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2605175..2605446 Replicon chromosome
Accession NZ_CP060867
Organism Escherichia coli strain EC29

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2605213..2605316 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2605175..2605446 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9211_RS12600 2602332..2603771 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H9211_RS12605 2603889..2604125 + 237 WP_001295499.1 YebV family protein -
H9211_RS12610 2604230..2604421 + 192 WP_000457842.1 YebW family protein -
H9211_RS12615 2604422..2605078 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2605175..2605446 + 272 - - Antitoxin
- 2605213..2605316 - 104 - - Toxin
H9211_RS12620 2605474..2605815 - 342 WP_000976476.1 YebY family protein -
H9211_RS12625 2605828..2606700 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H9211_RS12630 2606704..2607078 - 375 WP_000168747.1 CopC domain-containing protein YobA -
H9211_RS12635 2607217..2607447 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H9211_RS12640 2607549..2608205 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
H9211_RS12645 2608229..2608891 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T171229 NZ_CP060867:c2605316-2605213 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT171229 NZ_CP060867:2605175-2605446 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References