171048

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 716620..717201 Replicon chromosome
Accession NZ_CP060818
Organism Pantoea ananatis strain Lstri

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag IAQ00_RS03490 Protein ID WP_142392809.1
Coordinates 716998..717201 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag IAQ00_RS03485 Protein ID WP_252294211.1
Coordinates 716620..716970 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAQ00_RS03440 (IAQ00_03430) 711754..712578 + 825 WP_102023296.1 DUF932 domain-containing protein -
IAQ00_RS03445 (IAQ00_03435) 712787..713497 + 711 WP_227448141.1 DeoR family transcriptional regulator -
IAQ00_RS03450 (IAQ00_03440) 713523..714059 + 537 WP_035343370.1 DUF4339 domain-containing protein -
IAQ00_RS03455 (IAQ00_03445) 714101..714538 + 438 WP_035343367.1 hypothetical protein -
IAQ00_RS03460 (IAQ00_03450) 714605..715015 + 411 WP_193149470.1 hypothetical protein -
IAQ00_RS03465 (IAQ00_03455) 715093..715327 + 235 Protein_672 DUF905 domain-containing protein -
IAQ00_RS03470 (IAQ00_03460) 715413..715871 + 459 WP_090460851.1 antirestriction protein -
IAQ00_RS03475 (IAQ00_03465) 715880..716362 + 483 WP_252294209.1 DNA repair protein RadC -
IAQ00_RS03480 (IAQ00_03470) 716376..716597 + 222 WP_035343354.1 DUF987 domain-containing protein -
IAQ00_RS03485 (IAQ00_03475) 716620..716970 + 351 WP_252294211.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
IAQ00_RS03490 (IAQ00_03480) 716998..717201 + 204 WP_142392809.1 TA system toxin CbtA family protein Toxin
IAQ00_RS03495 (IAQ00_03485) 717188..717475 + 288 WP_224753023.1 hypothetical protein -
IAQ00_RS03500 (IAQ00_03490) 717589..717930 + 342 WP_252294213.1 TA system toxin CbtA family protein -
IAQ00_RS03505 (IAQ00_03495) 718045..718878 + 834 WP_252294215.1 DUF4942 domain-containing protein -
IAQ00_RS03515 (IAQ00_03505) 719356..719871 + 516 WP_058706414.1 G/U mismatch-specific DNA glycosylase -
IAQ00_RS03520 (IAQ00_03510) 719943..721787 - 1845 WP_028723590.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - rfaE 662163..756717 94554


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-51)

Antitoxin

Antitoxin CbeA

(15-115)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 7483.74 Da        Isoelectric Point: 4.4808

>T171048 WP_142392809.1 NZ_CP060818:716998-717201 [Pantoea ananatis]
MKILPETIRRVTMPYPLPGGVWLMLLISLLLQSCGLTLSGTLFNDENVILKNEAGTYPNTEGNYDEK

Download         Length: 204 bp

>T171048 NZ_CP077820:516594-517127 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 13112.01 Da        Isoelectric Point: 7.3718

>AT171048 WP_252294211.1 NZ_CP060818:716620-716970 [Pantoea ananatis]
MSNKTPTASNHTKAPWWGLKRDITPCFGARLVQEGNCLHYLADRTSIAGTFNDAELCHQDQDFPVLMKQMELMLTSGELN
PRHQHSVMLYVKGLTCEADTLGSHGYVYIVIYPTKR

Download         Length: 351 bp

>AT171048 NZ_CP077820:516317-516583 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References