Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1047787..1048343 Replicon chromosome
Accession NZ_CP060817
Organism Xanthomonas oryzae pv. oryzae strain C9-3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H9N23_RS04870 Protein ID WP_229001948.1
Coordinates 1048092..1048343 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag H9N23_RS04865 Protein ID WP_011408759.1
Coordinates 1047787..1048065 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9N23_RS04840 (H9N23_04830) 1042904..1043461 - 558 WP_011259349.1 DNA-3-methyladenine glycosylase -
H9N23_RS04845 (H9N23_04835) 1043611..1044576 - 966 WP_109181928.1 IS1595-like element ISXo5 family transposase -
H9N23_RS04850 (H9N23_04840) 1045157..1046341 + 1185 WP_011408760.1 IS256-like element IS1113 family transposase -
H9N23_RS04855 (H9N23_04850) 1047247..1047591 + 345 WP_199285675.1 hypothetical protein -
H9N23_RS04865 (H9N23_04855) 1047787..1048065 + 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
H9N23_RS04870 (H9N23_04860) 1048092..1048343 + 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9N23_RS04875 (H9N23_04865) 1048420..1048674 + 255 WP_198912806.1 hypothetical protein -
H9N23_RS23210 1048667..1048801 + 135 WP_011051575.1 hypothetical protein -
H9N23_RS04880 (H9N23_04870) 1048870..1049124 + 255 WP_223293127.1 hypothetical protein -
H9N23_RS23215 1049341..1049460 + 120 Protein_921 IS3 family transposase -
H9N23_RS23220 1049429..1049557 + 129 WP_012444694.1 hypothetical protein -
H9N23_RS04890 (H9N23_04885) 1049988..1050389 - 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
H9N23_RS04895 (H9N23_04890) 1050611..1050787 + 177 Protein_924 DUF3606 domain-containing protein -
H9N23_RS04905 (H9N23_04900) 1051069..1051406 + 338 Protein_925 ATP-dependent DNA ligase -
H9N23_RS04910 (H9N23_04905) 1051482..1052573 - 1092 WP_113195651.1 ribonuclease D -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T171044 WP_229001948.1 NZ_CP060817:1048092-1048343 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T171044 NZ_CP077818:c5123909-5123807 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT171044 WP_011408759.1 NZ_CP060817:1047787-1048065 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT171044 NZ_CP077818:5123800-5123945 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References