Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1980573..1980717 Replicon chromosome
Accession NZ_CP060807
Organism Klebsiella variicola strain KP2757

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1980609..1980711 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1980573..1980717 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAP99_RS09575 1975703..1977763 + 2061 WP_187726368.1 oligopeptidase B -
IAP99_RS09580 1977767..1978426 - 660 WP_008804267.1 exodeoxyribonuclease X -
IAP99_RS09585 1978505..1978735 - 231 WP_012541260.1 DNA polymerase III subunit theta -
IAP99_RS09590 1978849..1979223 + 375 WP_016161388.1 CopC domain-containing protein YobA -
IAP99_RS09595 1979227..1980096 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
IAP99_RS09600 1980113..1980451 + 339 WP_008804271.1 YebY family protein -
- 1980573..1980717 - 145 - - Antitoxin
- 1980609..1980711 + 103 - - Toxin
IAP99_RS09605 1981096..1981239 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
IAP99_RS09610 1981343..1982311 - 969 WP_162493241.1 VirK/YbjX family protein -
IAP99_RS09615 1982468..1983121 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
IAP99_RS09620 1983118..1983309 - 192 WP_002911395.1 YebW family protein -
IAP99_RS09625 1983407..1983646 - 240 WP_002911393.1 YebV family protein -
IAP99_RS09630 1983762..1985195 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T171020 NZ_CP060807:1980609-1980711 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT171020 NZ_CP060807:c1980717-1980573 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References