Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 4536176..4536846 | Replicon | chromosome |
| Accession | NZ_CP060783 | ||
| Organism | Diaphorobacter aerolatus strain KACC 16536 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | H9K75_RS21270 | Protein ID | WP_187724041.1 |
| Coordinates | 4536176..4536595 (-) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | H9K75_RS21275 | Protein ID | WP_187726135.1 |
| Coordinates | 4536592..4536846 (-) | Length | 85 a.a. |
Genomic Context
Location: 4531911..4533686 (1776 bp)
Type: Others
Protein ID: WP_187724039.1
Type: Others
Protein ID: WP_187724039.1
Location: 4533722..4536148 (2427 bp)
Type: Others
Protein ID: WP_187724040.1
Type: Others
Protein ID: WP_187724040.1
Location: 4536176..4536595 (420 bp)
Type: Toxin
Protein ID: WP_187724041.1
Type: Toxin
Protein ID: WP_187724041.1
Location: 4536592..4536846 (255 bp)
Type: Antitoxin
Protein ID: WP_187726135.1
Type: Antitoxin
Protein ID: WP_187726135.1
Location: 4537201..4539106 (1906 bp)
Type: Others
Protein ID: Protein_4184
Type: Others
Protein ID: Protein_4184
Location: 4539587..4539859 (273 bp)
Type: Others
Protein ID: WP_043387285.1
Type: Others
Protein ID: WP_043387285.1
Location: 4540172..4540741 (570 bp)
Type: Others
Protein ID: WP_187724042.1
Type: Others
Protein ID: WP_187724042.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H9K75_RS21260 | 4531911..4533686 | - | 1776 | WP_187724039.1 | type I restriction-modification system subunit M | - |
| H9K75_RS21265 | 4533722..4536148 | - | 2427 | WP_187724040.1 | DEAD/DEAH box helicase family protein | - |
| H9K75_RS21270 | 4536176..4536595 | - | 420 | WP_187724041.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| H9K75_RS21275 | 4536592..4536846 | - | 255 | WP_187726135.1 | Arc family DNA-binding protein | Antitoxin |
| H9K75_RS21285 | 4537201..4539106 | - | 1906 | Protein_4184 | SurA N-terminal domain-containing protein | - |
| H9K75_RS21295 | 4539587..4539859 | - | 273 | WP_043387285.1 | HU family DNA-binding protein | - |
| H9K75_RS21300 | 4540172..4540741 | - | 570 | WP_187724042.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 14764.23 Da Isoelectric Point: 5.8324
>T170961 WP_187724041.1 NZ_CP060783:c4536595-4536176 [Diaphorobacter aerolatus]
MILLDTNVMLEPLRHAPEPRVIEWIDAQAMDTLFLSAITVAELRAGVVLLPAGKRRACLQENLEKRVLPLFAGRVLPFDL
ACTQAYAALMAKARAVGTAISSADAYIAAIASANGFAVATRDTSLFEAAGAGVINPWQG
MILLDTNVMLEPLRHAPEPRVIEWIDAQAMDTLFLSAITVAELRAGVVLLPAGKRRACLQENLEKRVLPLFAGRVLPFDL
ACTQAYAALMAKARAVGTAISSADAYIAAIASANGFAVATRDTSLFEAAGAGVINPWQG
Download Length: 420 bp
>T170961 NZ_CP077806:c3317110-3316577 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9417.77 Da Isoelectric Point: 5.7268
>AT170961 WP_187726135.1 NZ_CP060783:c4536846-4536592 [Diaphorobacter aerolatus]
MAMLTVRNLPEEVHRALRVRAAQHGQSMEAEVREILESAISPKGRVKLGSLLADMGRQAKLSDEEFAVFEQVRDETPARP
VSFE
MAMLTVRNLPEEVHRALRVRAAQHGQSMEAEVREILESAISPKGRVKLGSLLADMGRQAKLSDEEFAVFEQVRDETPARP
VSFE
Download Length: 255 bp
>AT170961 NZ_CP077806:c3317387-3317121 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA