Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3381506..3381651 Replicon chromosome
Accession NZ_CP060744
Organism Klebsiella pneumoniae strain KP120

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3381513..3381615 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3381506..3381651 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAI03_RS16470 3377039..3378472 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IAI03_RS16475 3378588..3378827 + 240 WP_002911393.1 YebV family protein -
IAI03_RS16480 3378925..3379116 + 192 WP_002911395.1 YebW family protein -
IAI03_RS16485 3379113..3379766 - 654 WP_071570906.1 protein-serine/threonine phosphatase -
IAI03_RS16490 3379923..3380891 + 969 WP_168786284.1 VirK/YbjX family protein -
IAI03_RS16495 3380996..3381139 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3381506..3381651 + 146 - - Antitoxin
- 3381513..3381615 - 103 - - Toxin
IAI03_RS16500 3381774..3382112 - 339 WP_004189269.1 YebY family protein -
IAI03_RS16505 3382129..3382998 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
IAI03_RS16510 3383002..3383376 - 375 WP_004151448.1 CopC domain-containing protein YobA -
IAI03_RS16515 3383489..3383719 + 231 WP_002911406.1 DNA polymerase III subunit theta -
IAI03_RS16520 3383798..3384457 + 660 WP_187475335.1 exodeoxyribonuclease X -
IAI03_RS16525 3384461..3386521 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T170917 NZ_CP060744:c3381615-3381513 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT170917 NZ_CP060744:3381506-3381651 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References