Detailed information of TA system TA170875

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3638382..3639035
• Replicon: chromosome
• Accession: NZ_CP060732
• Organism: Acinetobacter baumannii strain abA1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: H7H20_RS17585
• Protein ID: WP_000607077.1
• Coordinates: 3638382..3638771 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: H7H20_RS17590
• Protein ID: WP_001288210.1
• Coordinates: 3638778..3639035 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H7H20_RS17570	3633500..3635695	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
H7H20_RS17575	3635883..3636449	-	567	WP_000651538.1	rhombosortase	-
H7H20_RS17580	3636527..3637612	-	1086	WP_000049106.1	hypothetical protein	-
H7H20_RS17585	3638382..3638771	-	390	WP_000607077.1	membrane protein	Toxin
H7H20_RS17590	3638778..3639035	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
H7H20_RS17595	3639223..3640395	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
H7H20_RS17600	3640444..3641934	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
H7H20_RS17605	3642116..3642493	-	378	WP_001216380.1	50S ribosomal protein L17	-
H7H20_RS17610	3642512..3643519	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T170875 WP_000607077.1 NZ_CP060732:c3638771-3638382 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T170875 NZ_CP077760:c2359632-2359321 [Salmonella enterica subsp. enterica serovar Gallinarum]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGATGAATGAGAGGTGGTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT170875 WP_001288210.1 NZ_CP060732:c3639035-3638778 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT170875 NZ_CP077760:c2359320-2359030 [Salmonella enterica subsp. enterica serovar Gallinarum]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7