Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-HTH_XRE
Location 4234870..4235623 Replicon chromosome
Accession NZ_CP060726
Organism Providencia rettgeri strain YPR25

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H9X60_RS19510 Protein ID WP_096864327.1
Coordinates 4235189..4235623 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H9X60_RS19505 Protein ID WP_004905885.1
Coordinates 4234870..4235199 (-) Length 110 a.a.

Genomic Context


H9X60_RS19495H9X60_RS19500H9X60_RS19490H9X60_RS19505H9X60_RS19510H9X60_RS19515H9X60_RS19520
Location: 4232444..4234129 (1686 bp)
Type: Others
Protein ID: WP_004905883.1
Location: 4234149..4234865 (717 bp)
Type: Others
Protein ID: WP_004905884.1
Location: 4230815..4231786 (972 bp)
Type: Others
Protein ID: WP_004905881.1
Location: 4234870..4235199 (330 bp)
Type: Antitoxin
Protein ID: WP_004905885.1
Location: 4235189..4235623 (435 bp)
Type: Toxin
Protein ID: WP_096864327.1
Location: 4235732..4237663 (1932 bp)
Type: Others
Protein ID: WP_004905887.1
Location: 4237834..4238700 (867 bp)
Type: Others
Protein ID: WP_004905888.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H9X60_RS194904230815..4231786-972WP_004905881.1efflux RND transporter periplasmic adaptor subunit-
H9X60_RS194954232444..4234129+1686WP_004905883.1sensor histidine kinase-
H9X60_RS195004234149..4234865+717WP_004905884.1two-component system response regulator BtsR-
H9X60_RS195054234870..4235199-330WP_004905885.1helix-turn-helix domain-containing proteinAntitoxin
H9X60_RS195104235189..4235623-435WP_096864327.1type II toxin-antitoxin system RelE/ParE family toxinToxin
H9X60_RS195154235732..4237663-1932WP_004905887.1DEAD/DEAH family ATP-dependent RNA helicase-
H9X60_RS195204237834..4238700-867WP_004905888.1lipoprotein NlpI-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(19-139)

Antitoxin

(53-93)


Sequences


Toxin        


Download         Length: 145 a.a.        Molecular weight: 16141.82 Da        Isoelectric Point: 9.3330

>T170869 WP_096864327.1 NZ_CP060726:c4235623-4235189 [Providencia rettgeri]
MALATIVIGTTWRVVVAFYKISSFKRSTKKIKIMDKHLLKAANEVLAGVYEADLGSGVIKKRIAINGKGKSGGVRVIIFF
KVSHHLFFADGWEKCNIAAKGVKEIEDDELDAYKNLSRLFLNYTDDKIADLVLHNILEELTDEQ

Download         Length: 435 bp

>T170869 NZ_CP077760:1172767-1172985 [Salmonella enterica subsp. enterica serovar Gallinarum]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12235.50 Da        Isoelectric Point: 10.3803

>AT170869 WP_004905885.1 NZ_CP060726:c4235199-4234870 [Providencia rettgeri]
MSNKLENMLELAKELHQVDAAPKSLVTDLEQKVGNRKINNKIKVVPMMSGAQIKQLRAQYGMSQAMLALALGMSKESVSK
WEREEKKPSGPALRMLHLIEQRGPEILII

Download         Length: 330 bp

>AT170869 NZ_CP077760:1172365-1172739 [Salmonella enterica subsp. enterica serovar Gallinarum]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References