Detailed information of TA system TA170868

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 4227788..4228373
• Replicon: chromosome
• Accession: NZ_CP060726
• Organism: Providencia rettgeri strain YPR25

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: H9X60_RS19470
• Protein ID: WP_110591061.1
• Coordinates: 4227788..4228105 (-)
• Length: 106 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: H9X60_RS19475
• Protein ID: WP_172767478.1
• Coordinates: 4228086..4228373 (-)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H9X60_RS19440	4223491..4223742	-	252	WP_172767476.1	DUF1471 domain-containing protein	-
H9X60_RS19445	4224013..4224351	+	339	WP_004905864.1	GIY-YIG nuclease family protein	-
H9X60_RS19450	4224324..4224827	-	504	WP_172767477.1	N-acetyltransferase	-
H9X60_RS19455	4224821..4225345	-	525	WP_004905868.1	SCP2 domain-containing protein	-
H9X60_RS19460	4225860..4226855	+	996	WP_094961644.1	U32 family peptidase	-
H9X60_RS19465	4226873..4227748	+	876	WP_164565609.1	U32 family peptidase	-
H9X60_RS19470	4227788..4228105	-	318	WP_110591061.1	type II toxin-antitoxin system YafQ family toxin	Toxin
H9X60_RS19475	4228086..4228373	-	288	WP_172767478.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
H9X60_RS19480	4228504..4229658	-	1155	WP_004905877.1	ABC transporter permease	-
H9X60_RS19485	4229658..4230803	-	1146	WP_004905879.1	ABC transporter permease	-
H9X60_RS19490	4230815..4231786	-	972	WP_004905881.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (14-104)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-87)

Sequences

Toxin

Protein

• Length: 106 a.a.
• Molecular weight: 12206.90 Da
• Isoelectric Point: 8.4953

>T170868 WP_110591061.1 NZ_CP060726:c4228105-4227788 [Providencia rettgeri]
MTQKPSNKRAKQPRQVAYTPTFKESWERYNRAGRRDMNAAVLVMEILFSQKIIPKEYLDHELEGHEWQGARELHIGGDFL
LVYRLSDKGNLITFVDIGSHSELFG

Nucleotide

• Length: 318 bp

>T170868 NZ_CP077760:c436149-436046 [Salmonella enterica subsp. enterica serovar Gallinarum]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATCTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10789.47 Da
• Isoelectric Point: 5.1969

>AT170868 WP_172767478.1 NZ_CP060726:c4228373-4228086 [Providencia rettgeri]
MSTLLKTTDVRSRIDEQLKAEATSVLQDCGLTISAAIRLFLEQVVQEQRVPFEIKRKQPSLKTTLALKEAKAIEQYYDSI
NEMMVELSKVDSEAK

Nucleotide

• Length: 288 bp

>AT170868 NZ_CP077760:436044-436189 [Salmonella enterica subsp. enterica serovar Gallinarum]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAGATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG