Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1349982..1350486 Replicon chromosome
Accession NZ_CP060723
Organism Pedobacter roseus strain KACC 11594

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag H9L23_RS06070 Protein ID WP_187594124.1
Coordinates 1350232..1350486 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag H9L23_RS06065 Protein ID WP_187594123.1
Coordinates 1349982..1350239 (+) Length 86 a.a.

Genomic Context

H9L23_RS06065H9L23_RS06070H9L23_RS06075H9L23_RS06060H9L23_RS06080
Location: 1349982..1350239 (258 bp)
Type: Antitoxin
Protein ID: WP_187594123.1
Location: 1350232..1350486 (255 bp)
Type: Toxin
Protein ID: WP_187594124.1
Location: 1350497..1352157 (1661 bp)
Type: Others
Protein ID: Protein_1185
Location: 1349235..1349855 (621 bp)
Type: Others
Protein ID: WP_187594122.1
Location: 1352851..1354299 (1449 bp)
Type: Others
Protein ID: WP_187594125.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H9L23_RS060601349235..1349855-621WP_187594122.1threonylcarbamoyl-AMP synthase-
H9L23_RS060651349982..1350239+258WP_187594123.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
H9L23_RS060701350232..1350486+255WP_187594124.1Txe/YoeB family addiction module toxinToxin
H9L23_RS060751350497..1352157+1661Protein_1185FMN-binding glutamate synthase family protein-
H9L23_RS060801352851..1354299-1449WP_187594125.1asparagine--tRNA ligase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10143.85 Da        Isoelectric Point: 9.0444

>T170860 WP_187594124.1 NZ_CP060723:1350232-1350486 [Pedobacter roseus]
MIKLFLDGAWEDCLYWQLVDKSVLKKINALIKEIERTPFEGTGKPEPLKHQYSGWWSRRINLEHRLVYKVEDNKIILLQC
RYHT

Download         Length: 255 bp

>T170860 NZ_CP077755:2689680-2690042 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9859.13 Da        Isoelectric Point: 4.8102

>AT170860 WP_187594123.1 NZ_CP060723:1349982-1350239 [Pedobacter roseus]
MEITNYTSFRQSLKSYLDKVFTNHTPLFVTRAKGEDVVVLSKADYDSMQETFYLLKSPKNAMRLEQGLKDYEDGLAKEKD
LIDND

Download         Length: 258 bp

>AT170860 NZ_CP077755:2689513-2689683 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References