170849

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1550924..1551324 Replicon chromosome
Accession NZ_CP060711
Organism Thermomonas brevis strain KACC 16975

Toxin (Protein)


Gene name EcnB Uniprot ID -
Locus tag H9L17_RS07290 Protein ID WP_187571664.1
Coordinates 1550924..1551055 (-) Length 44 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag H9L17_RS07295 Protein ID WP_187571665.1
Coordinates 1551172..1551324 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9L17_RS07260 1546048..1546434 + 387 WP_187571659.1 VOC family protein -
H9L17_RS07265 1546439..1547749 - 1311 WP_187571660.1 metallophosphoesterase -
H9L17_RS07270 1547833..1548345 + 513 WP_187571661.1 MarR family transcriptional regulator -
H9L17_RS07275 1548352..1548645 - 294 WP_187571887.1 hypothetical protein -
H9L17_RS07280 1548663..1549982 - 1320 WP_187571662.1 tryptophan--tRNA ligase -
H9L17_RS07285 1550107..1550892 + 786 WP_187571663.1 hypothetical protein -
H9L17_RS07290 1550924..1551055 - 132 WP_187571664.1 entericidin A/B family lipoprotein Toxin
H9L17_RS07295 1551172..1551324 - 153 WP_187571665.1 entericidin A/B family lipoprotein Antitoxin
H9L17_RS07300 1551420..1551899 - 480 WP_187571666.1 DUF421 domain-containing protein -
H9L17_RS07305 1552384..1555164 - 2781 WP_187571667.1 DNA polymerase I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 44 a.a.        Molecular weight: 4383.28 Da        Isoelectric Point: 9.4064

>T170849 WP_187571664.1 NZ_CP060711:c1551055-1550924 [Thermomonas brevis]
MNKTMKLAVLALTCMAFLAGCNTIAGAGKDIQKAGEKIEGAAK

Download         Length: 132 bp

>T170849 NZ_CP077741:c369467-369006 [Staphylococcus aureus]
ATGGGATTATATGAAGAAACTTTAATACAACATGATTATATTGAAATAAGAGAGGCTGATGTGCTTCCAGATAATTTGGA
TGGGGTATGGTTAGGAGATTTAATTTTAATAAAGCGTGGCTTATCAGATAGAGAAAAGGCAGGAATTCTCTTTGAAGAAT
TAGCACATAATAAACTTACATACGGTGATATAGCCGATTACTCGAAATTCAACAATCGCAAGTTCGAAAATTACGCAAGG
CGACACGGCTTTATCTCAGCAGTCCCGTTACGCGAAATTGTGGAAGCTTACAATTATGGTGTACGTAACTTGTATGAGTT
GTCTGAGTATCTGCAATTGAGTGAAGAATACATATTAGAAGCAATAGAACAATATAAAAAGATATATGGTATTGGGACTC
ACTACGGCGAATACTCAATTACATTTGAGCCATTGAGAGTTTTTAAATATAAAGAAATATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5399.45 Da        Isoelectric Point: 8.2766

>AT170849 WP_187571665.1 NZ_CP060711:c1551324-1551172 [Thermomonas brevis]
MKRMFATLILVMFVSAGLTACNTMAGAGKDVQKAGEKVEQKAEDCKDMKC

Download         Length: 153 bp

>AT170849 NZ_CP077741:c369794-369480 [Staphylococcus aureus]
ATGTGCTTTTCAAAAAGAATGAAACAATCAAGAGAAAAACAAGGTATGACTTTGGCCGAACTAGGAAGAAAAATTGGTAA
AACTGAAGCTACTGTACAGCGTTATGAAAGCGGAAATATCAAAAATTTAAAAAACGATACTATAGAAAGTATAGCTACTG
CATTAAATGTTAATCCTGCATATTTAATGGGGTGGGTTGAAGAAAACGATGATGAAGTACAACATCGTGCAGCTCACCTT
GAAGGAGAATTGACAGATGATGAATGGCAAAGAGTTTTAGATTATGCAGATTATATAAGAAGCAAACGTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References