Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 4822645..4823189 | Replicon | chromosome |
Accession | NZ_CP060704 | ||
Organism | Chitinimonas koreensis strain R2A43-10 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | H9L41_RS20400 | Protein ID | WP_028444852.1 |
Coordinates | 4822645..4822935 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | H9L41_RS20405 | Protein ID | WP_265583858.1 |
Coordinates | 4822923..4823189 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
H9L41_RS20380 (H9L41_20380) | 4817910..4819412 | + | 1503 | WP_028444856.1 | hypothetical protein | - |
H9L41_RS20385 (H9L41_20385) | 4819405..4820877 | + | 1473 | WP_028444855.1 | exodeoxyribonuclease I | - |
H9L41_RS20390 (H9L41_20390) | 4821124..4821513 | + | 390 | WP_028444854.1 | DUF488 family protein | - |
H9L41_RS20395 (H9L41_20395) | 4821744..4822616 | + | 873 | WP_034606071.1 | dTDP-4-dehydrorhamnose reductase | - |
H9L41_RS20400 (H9L41_20400) | 4822645..4822935 | - | 291 | WP_028444852.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
H9L41_RS20405 (H9L41_20405) | 4822923..4823189 | - | 267 | WP_265583858.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
H9L41_RS20410 (H9L41_20410) | 4823346..4823909 | - | 564 | WP_034606069.1 | DUF5610 domain-containing protein | - |
H9L41_RS20415 (H9L41_20415) | 4824107..4825522 | - | 1416 | WP_028444850.1 | FAD-dependent oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10944.50 Da Isoelectric Point: 9.3501
>T170760 WP_028444852.1 NZ_CP060704:c4822935-4822645 [Chitinimonas koreensis]
MPRLIWSPQALHDVQRLYRFLAANNADAARRAVKAIRDGVKLLASQPGVGRPAEEMEPEYREWLIDFGDSGYIALYRYDG
KTALILAVRHQREAGY
MPRLIWSPQALHDVQRLYRFLAANNADAARRAVKAIRDGVKLLASQPGVGRPAEEMEPEYREWLIDFGDSGYIALYRYDG
KTALILAVRHQREAGY
Download Length: 291 bp
>T170760 NZ_CP077699:c1313439-1313257 [Salmonella enterica subsp. enterica]
ATGAAATATAACGAGTTCAGGCGGTGGCTCATCCAACAGGGTGCAAAGTTCATAAATGCACCGGATGGCGGCAGCCATCA
GCGTGTCATACTGAACGGGAAAGAATCTGTATTTCCCTGCCATGGCGCCAAAGAAATGCCGGAGCCGCTCAGAAAGAAAA
TACTCAAGGATTTGGGGCTTTAA
ATGAAATATAACGAGTTCAGGCGGTGGCTCATCCAACAGGGTGCAAAGTTCATAAATGCACCGGATGGCGGCAGCCATCA
GCGTGTCATACTGAACGGGAAAGAATCTGTATTTCCCTGCCATGGCGCCAAAGAAATGCCGGAGCCGCTCAGAAAGAAAA
TACTCAAGGATTTGGGGCTTTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10103.28 Da Isoelectric Point: 5.1991
>AT170760 WP_265583858.1 NZ_CP060704:c4823189-4822923 [Chitinimonas koreensis]
VAIKIDPETRERIKRLAAARDRTPHWIMREAISQYVEREEKREALRQDGIMAWNAYHANGLHATADEADAWLAELEAGRD
VEPPECHG
VAIKIDPETRERIKRLAAARDRTPHWIMREAISQYVEREEKREALRQDGIMAWNAYHANGLHATADEADAWLAELEAGRD
VEPPECHG
Download Length: 267 bp
>AT170760 NZ_CP077699:c1313228-1312794 [Salmonella enterica subsp. enterica]
ATGTTTAACTATGCTGTGAAACCTGAGTATGATCCCGCAACAGAAAGCTGGGTTGTCACATGCCGGGATCTGCCACTATT
TAACTCCGTGAGTTTCAGCATTGACGATGCGCTTCTTGAGGCGGTTGATGGTGCCATCGTTGCACTCTCAATCGAAATCG
ACGCACGCCGTCCAGTCCCCATCGCCAGCCAGCCCGAAGAAGGGGAGTATGTCATTCATCTTCCCGTTCTGGTTGTGATG
AAAGCCGCGCTGCATAATGCAATGATTTCCACAGGGACACGAAAATCCGATCTTGCCCGAACTATGGGGATGAAAGGTCC
CCAGATAGATCGCCTCCTGGATGTTTGCCACTCATCGAAAGTGGAAACAGTAGAACTCGCTCTTCAGCAACTCAACCGGA
CTGTACAGATAAGCGTTGATAACGTTGCGGTATAA
ATGTTTAACTATGCTGTGAAACCTGAGTATGATCCCGCAACAGAAAGCTGGGTTGTCACATGCCGGGATCTGCCACTATT
TAACTCCGTGAGTTTCAGCATTGACGATGCGCTTCTTGAGGCGGTTGATGGTGCCATCGTTGCACTCTCAATCGAAATCG
ACGCACGCCGTCCAGTCCCCATCGCCAGCCAGCCCGAAGAAGGGGAGTATGTCATTCATCTTCCCGTTCTGGTTGTGATG
AAAGCCGCGCTGCATAATGCAATGATTTCCACAGGGACACGAAAATCCGATCTTGCCCGAACTATGGGGATGAAAGGTCC
CCAGATAGATCGCCTCCTGGATGTTTGCCACTCATCGAAAGTGGAAACAGTAGAACTCGCTCTTCAGCAACTCAACCGGA
CTGTACAGATAAGCGTTGATAACGTTGCGGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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