Detailed information of TA system TA170759

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3915959..3916490
• Replicon: chromosome
• Accession: NZ_CP060704
• Organism: Chitinimonas koreensis strain R2A43-10

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: H9L41_RS16325
• Protein ID: WP_028444707.1
• Coordinates: 3916200..3916490 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: H9L41_RS16320
• Protein ID: WP_028444706.1
• Coordinates: 3915959..3916210 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H9L41_RS16300 (H9L41_16300)	3912174..3913079	+	906	WP_028444702.1	50S ribosomal protein L3 N(5)-glutamine methyltransferase	-
H9L41_RS16305 (H9L41_16305)	3913275..3913817	-	543	WP_051318682.1	adenine phosphoribosyltransferase	-
H9L41_RS16310 (H9L41_16310)	3913888..3915177	-	1290	WP_028444704.1	NCS2 family permease	-
H9L41_RS16315 (H9L41_16315)	3915300..3915761	-	462	WP_245589159.1	low molecular weight protein-tyrosine-phosphatase	-
H9L41_RS16320 (H9L41_16320)	3915959..3916210	+	252	WP_028444706.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
H9L41_RS16325 (H9L41_16325)	3916200..3916490	+	291	WP_028444707.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H9L41_RS16330 (H9L41_16330)	3916518..3917801	-	1284	WP_028444708.1	haloacid dehalogenase-like hydrolase	-
H9L41_RS16335 (H9L41_16335)	3917939..3918739	-	801	WP_034605901.1	transporter substrate-binding domain-containing protein	-
H9L41_RS16340 (H9L41_16340)	3919197..3920909	+	1713	WP_028444710.1	gamma-glutamyltransferase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	3792491..4091415	298924

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-77)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10730.48 Da
• Isoelectric Point: 10.6254

>T170759 WP_028444707.1 NZ_CP060704:3916200-3916490 [Chitinimonas koreensis]
MSYELAFHPAALAEWRSLDGSVRKQLKTKLAERLEQPHVPAARVSGGADLYKIKLRALGYRLVYQVQDSRITVLVLAVGR
RDRNAAYVAALGRIEP

Nucleotide

• Length: 291 bp

>T170759 NZ_CP077699:938016-938429 [Salmonella enterica subsp. enterica]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CGCGCCAACACTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 8710.02 Da
• Isoelectric Point: 4.4982

>AT170759 WP_028444706.1 NZ_CP060704:3915959-3916210 [Chitinimonas koreensis]
METILANRSVGLSELKANPAAVMRAAETEPVAILNRNKPAGYVIGTAAWEAIAERLDNLALAELAAARLADGQAPVKVTL
DEL

Nucleotide

• Length: 252 bp

>AT170759 NZ_CP077699:937769-938035 [Salmonella enterica subsp. enterica]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA