170757

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2884058..2884626 Replicon chromosome
Accession NZ_CP060704
Organism Chitinimonas koreensis strain R2A43-10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H9L41_RS12010 Protein ID WP_028447086.1
Coordinates 2884058..2884432 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H9L41_RS12015 Protein ID WP_028447085.1
Coordinates 2884429..2884626 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9L41_RS11990 (H9L41_11990) 2879173..2879952 - 780 WP_028447088.1 transporter substrate-binding domain-containing protein -
H9L41_RS11995 (H9L41_11995) 2880104..2881120 + 1017 WP_028447087.1 heat-inducible transcriptional repressor HrcA -
H9L41_RS24755 2881274..2881450 - 177 WP_265583757.1 hypothetical protein -
H9L41_RS12000 (H9L41_12000) 2881520..2882362 + 843 Protein_2410 lytic murein transglycosylase B -
H9L41_RS12005 (H9L41_12005) 2882397..2883851 - 1455 WP_187523370.1 exonuclease domain-containing protein -
H9L41_RS12010 (H9L41_12010) 2884058..2884432 - 375 WP_028447086.1 type II toxin-antitoxin system VapC family toxin Toxin
H9L41_RS12015 (H9L41_12015) 2884429..2884626 - 198 WP_028447085.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
H9L41_RS12020 (H9L41_12020) 2884737..2888756 - 4020 WP_028447084.1 translocation/assembly module TamB domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-46)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13643.78 Da        Isoelectric Point: 6.3238

>T170757 WP_028447086.1 NZ_CP060704:c2884432-2884058 [Chitinimonas koreensis]
VILVDTSVWIDHLRQGDEQLRSLLESGSVHVHPMVVGELACGQLGARRQVLDLLAALPALPRAEDAEVLFFIEQRRLMGR
GIGYVDAHLLASTVMQPPARLWSRDKRLAGIAQELGCAFAEAQH

Download         Length: 375 bp

>T170757 NZ_CP077698:c1662-1348 [Salmonella enterica subsp. enterica]
ATGCAGTTCACTGTATACAGTAACACCGGAAAGAGCACCGTCTATCCCCTGCTGCTTGATGTAACCAGCGATATTATCGG
CCAGTTGAACCGCAGGATTGTGATCCCGCTGCTGCCTGTTGAAAAGTACCCAGGCAGCACCCGCCCGGAACGGCTGGTTC
CGCTTGTCAGACTGACCGACGATAAAGAATATGCAGTTATGACGCATGAAATGGCGAGTATTCCCGCCCGTTCTCTGGGG
GCTGCGTTCTGCGATGCTTCCCCTTATCGTACCGAAGTCAAAGCTGCGATTGATTTTCTTCTTGATGGTATTTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7296.32 Da        Isoelectric Point: 9.4779

>AT170757 WP_028447085.1 NZ_CP060704:c2884626-2884429 [Chitinimonas koreensis]
MRTTLNLDDALLDQAQRLSGLQERSALMREALLALIQRESARRLARLGGSEPDLQAVPRRRDGEP

Download         Length: 198 bp

>AT170757 NZ_CP077698:c1901-1665 [Salmonella enterica subsp. enterica]
ATGGCAACAACACAACGAGCAACGCAAAGCGTTACTATGACTGTAGAACGTGCCTTACTCAGCCGTGCGCGTGAGGCTGG
AATTAATCTCAGTGCCACTCTGACCGCAGCCCTTGACGCTGAACTACGCCAGTATGAAGCGAAAAAATGGCAGGAGGAAA
ACAACGAAGCGCTGGAAGCTCTTAATCGTTTTCACGATGAACATGGTTGTTTCAGCGATGAGTACAGGACATTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References