Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 1371928..1372457 Replicon plasmid Plas1
Accession NZ_CP060702
Organism Ralstonia solanacearum strain FJAT454.F50-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H9X76_RS24055 Protein ID WP_016722340.1
Coordinates 1372230..1372457 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H9X76_RS24050 Protein ID WP_016722339.1
Coordinates 1371928..1372233 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9X76_RS24025 1367034..1367315 - 282 WP_016722336.1 hypothetical protein -
H9X76_RS24030 1367446..1367730 - 285 WP_011003391.1 hypothetical protein -
H9X76_RS24035 1368182..1369167 + 986 WP_182137725.1 IS5 family transposase -
H9X76_RS24040 1369312..1369463 + 152 Protein_1078 IS5/IS1182 family transposase -
H9X76_RS24045 1370402..1371715 - 1314 WP_038938025.1 metabolite/H+ symporter -
H9X76_RS24050 1371928..1372233 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
H9X76_RS24055 1372230..1372457 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9X76_RS24060 1372612..1373811 - 1200 WP_016726513.1 MFS transporter -
H9X76_RS24065 1373938..1374759 - 822 WP_011003398.1 GntR family transcriptional regulator -
H9X76_RS24070 1374937..1375488 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
H9X76_RS24075 1375621..1376220 + 600 WP_016722344.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB / adeG / cheY / cheB / cheW / motA / cyaB / flgC / flgG / fliM / fliG / fliI 1..2074598 2074598


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T170748 WP_016722340.1 NZ_CP060702:c1372457-1372230 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T170748 NZ_CP077696:c1886144-1885815 [Salmonella enterica subsp. enterica]
ATGAACTACACTATTGAGTACTACAACGAGGAAGTCCGGATTGAGGTGGATCAGCTTCCATTGAGTATGCGAGCCAGATA
TCAGCACCTTGTTGAACGAATGAAGGTGTATGGCAGCAATCTCGGAGAACCTCACACCAGCGCCTTTGGTGATGGGCTTT
TTGAGCTTCGGATTAAAGGCAGCGATGGCATCGCTCGCGTTTTTTACTGCACCCTGGCAGGGAAGCGCATCGTCATGCTG
CACAGCTTTATAAAGAAGACTCAGAAAACCCCTGTAGCTGAACGCAAAAAGGCAGAAACCAGAATGAAGGAGGTTAAGCA
TGACTGGTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT170748 WP_016722339.1 NZ_CP060702:c1372233-1371928 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT170748 NZ_CP077696:c1885825-1885517 [Salmonella enterica subsp. enterica]
ATGACTGGTAAACGTAATGCGCCAACTATAACGCACGATGAAATGGCCGCTAAATGGATGGAAGACCCAGCGTTCAAAGC
TGAATATGACGCCATTGCTGATGAGTTCGCGTTACTTGACGAAATGCTGGCCGCACGTAAAGAAGCAGGTCTCACCCAGG
CTGAAGTTGCTGAACGGATGGGAACAAAAGCCACTGCTATAACCAGAATGGAAAGCAACCTTGCTGCTGGCGTCAGCGGA
CCATCTTTTACTACGCTGAAAAAGTTCGCACAGGCAACCGGGAAAAAACTCCAGATCCGCTTCGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References