Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 321347..321934 Replicon chromosome
Accession NZ_CP060698
Organism Amniculibacterium sp. G2-70

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag H9Q20_RS01445 Protein ID WP_187478128.1
Coordinates 321347..321646 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H9Q20_RS01450 Protein ID WP_187478129.1
Coordinates 321650..321934 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9Q20_RS01430 316762..318969 + 2208 WP_187478125.1 RelA/SpoT family protein -
H9Q20_RS01435 318979..320145 + 1167 WP_187478126.1 Na+/H+ antiporter NhaA -
H9Q20_RS01440 320468..321124 + 657 WP_187478127.1 metal-dependent transcriptional regulator -
H9Q20_RS01445 321347..321646 + 300 WP_187478128.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9Q20_RS01450 321650..321934 + 285 WP_187478129.1 putative addiction module antidote protein Antitoxin
H9Q20_RS01455 322142..322489 + 348 WP_124640467.1 type II toxin-antitoxin system RelE/ParE family toxin -
H9Q20_RS01460 322489..322797 + 309 WP_124640468.1 helix-turn-helix domain-containing protein -
H9Q20_RS01465 322938..324308 - 1371 WP_124640470.1 tetratricopeptide repeat protein -
H9Q20_RS01470 324371..326932 - 2562 WP_187478130.1 DNA gyrase subunit A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11784.76 Da        Isoelectric Point: 10.2372

>T170739 WP_187478128.1 NZ_CP060698:321347-321646 [Amniculibacterium sp. G2-70]
MYFIEKTAEFDKWLRKLKDTRAKAKVLFRIQKLEKDEHFGDYEPVGNGIRELKINYAKGYRIYFKETDGKIIILLIGGDK
SSQQKDIEKAKDIWNKIKK

Download         Length: 300 bp

>T170739 NZ_CP077693:c4393556-4393272 [Salmonella enterica subsp. enterica]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTCGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10249.71 Da        Isoelectric Point: 4.4143

>AT170739 WP_187478129.1 NZ_CP060698:321650-321934 [Amniculibacterium sp. G2-70]
METSKFDIADYLDSNEMIAEYLNEVLENGYDSEIITAIGNIAKAIGMTKIAEETGLSRPSLYKALSEGAKPQFSTIMKVL
RAVGGQIQINPAHI

Download         Length: 285 bp

>AT170739 NZ_CP077693:c4393788-4393546 [Salmonella enterica subsp. enterica]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCATTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References