Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) toxTA/Tad-couple_hipB
Location 3471733..3472382 Replicon chromosome
Accession NZ_CP060633
Organism Simiaoa sunii strain NSJ-8

Toxin (Protein)


Gene name toxT Uniprot ID -
Locus tag H9Q77_RS16120 Protein ID WP_249326256.1
Coordinates 3471733..3472098 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name toxA Uniprot ID -
Locus tag H9Q77_RS16125 Protein ID WP_118545257.1
Coordinates 3472095..3472382 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9Q77_RS16105 (H9Q77_16105) 3467122..3467943 - 822 WP_249326253.1 Cof-type HAD-IIB family hydrolase -
H9Q77_RS16110 (H9Q77_16110) 3468039..3469694 - 1656 WP_249326254.1 peptidylprolyl isomerase -
H9Q77_RS16115 (H9Q77_16115) 3469770..3471443 - 1674 WP_249326255.1 M3 family oligoendopeptidase -
H9Q77_RS16120 (H9Q77_16120) 3471733..3472098 + 366 WP_249326256.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9Q77_RS16125 (H9Q77_16125) 3472095..3472382 + 288 WP_118545257.1 helix-turn-helix transcriptional regulator Antitoxin
H9Q77_RS16130 (H9Q77_16130) 3472573..3473760 - 1188 WP_249326257.1 flagellin -
H9Q77_RS16135 (H9Q77_16135) 3473941..3474210 - 270 WP_022155041.1 carbon storage regulator -
H9Q77_RS16140 (H9Q77_16140) 3474328..3474909 + 582 WP_118551622.1 tyrosine-type recombinase/integrase -
H9Q77_RS16145 (H9Q77_16145) 3475161..3476081 + 921 WP_249326258.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(37-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14747.07 Da        Isoelectric Point: 10.0555

>T170524 WP_249326256.1 NZ_CP060633:3471733-3472098 [Simiaoa sunii]
MMYDIEYYFDKNGYSAISDYFADLAKKSIYSKTIRIQKNKIFAYIKALKEYGTRIGNPIVKHIQGDLWELRPLNNRIFFF
YWKDNKFVLLHYYIKKTQKTPHREISKALAYMHDWLERNNS

Download         Length: 366 bp

>T170524 NZ_CP077422:4916099-4917418 [Dickeya dadantii]
ATGGCTGCGCTCGATGTTTACATGAACGGCTACCGGGTGGGGATTCTGACCAAAACGGGCAGTGGCGCACATCATTTTTC
CTACGATGCGAACTGGCTCGGGTTGCCGGGGAACCGACCCATTTCGCTCTCTATGCCACTACGCCATCAGCCCTATCAAG
GTGATGAAGTTTATAATTTCTTCGACAATTTGTTGCCGGATAACCCAGATATCAGAAGGCGAATTGTTGCCAGGCATCAT
GCGGATTCCACCCAGCCGTTTGATCTGCTGGCTAAAGTGGGGCAAGACAGTGTCGGGGCGTTGCAATTGGTGCCGCAGGG
TATTCCTGCTCGCGATATAAAACAGATTGAATATAAAACATTATCCGAGCAACAGCTTGAAAGCATACTGTCGGGATATC
TGTCTGATGCGCCGCTGGGGATGATTGATACAGAAGACGATTTTCGAATCTCTATTGCTGGCGCACAGGAAAAGACGGCG
CTACTGTATCTGGATAATCACTGGTGCCTGCCCTTCAATACCACACCAACTACCCACATCATCAAACTACCGATTGGTAA
AATCGAGAGTCATTCTTACTCAATTGATATGTCTGACAGCGTTGAAAATGAGTACCTGTGCCTGCTCATTGCCAGGGCAT
TTGGGCTACCGGTGCCGCACTGTTTTATGATCAAAGCTGGCAAGATAAAAGCGCTGGCCGTGGAGCGTTTTGATCGCAAA
TATGCTTCGGATGGCAGTTGGATTATGCGGCTGCCGCAGGAAGATTTTTGTCAGGTATTAAACGTGCCTTCCGCACTAAA
ATATGAAAATCATGGTGGACCAGGTATTTCCGCTATTATGTCGTATCTATTAGGCGCGGTTGATCCACAAAGAGATCGTT
ATAGTTTTATGAAGGCGCAGGTGCTGTTTTGGCTATTGGCTGCAACGGATGGTCATGCGAAAAACTTTTCCTTGTTTATT
GAGTCTGAGGGACGATATCGCCTCACGCCTTTCTATGACATTCTCTCTATGTACCCGGCATTTGGCGGCCGGGGAATTGA
CCGTAGAGATGCGAAGCTAGCGATGGGGCTGGCTGGCACCAGAGGTAAGAAATACCATATCGAGAAGATATTCCCTCGGC
ATTTTTTCCAAACGGCAAAGGCGGTTGGCTTTGCCAGAGAATCAATGGAACGCATTCTGACTGAATTTTCACAGACGGTT
GATTCTGTCATCGTGAGTGTCAGAAACCAACTGCCTGCGGATTTTCCCACTCCTATTCGCGATGCGATCCTGGGAGGGCT
ACAGACTAGATCGAGGCGATTGACGACGGGCTGGGAATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10976.74 Da        Isoelectric Point: 5.2187

>AT170524 WP_118545257.1 NZ_CP060633:3472095-3472382 [Simiaoa sunii]
MKKYKNFDEMFNDNDYVSEEDREIINLEVKLIGKMIEAREKQGLTQRDLAKISGVKQPAIARIESLRSTPQLDTLLKVLI
PLGYSLEIIPLQKEN

Download         Length: 288 bp

>AT170524 NZ_CP077422:4915833-4916099 [Dickeya dadantii]
ATGAAAGTCACCAACGCCAAACAGCTTAGCAGCTATCTGAAAGATGTTCGTATCATGCAGAAGCTTTCACAAGGGAAAGT
GGCCAGTAAAGTGGGTATTCGCCAGGACACAGTATCCAGCTTCGAACAACATCCTGATTCCACCAAGCTGGAAACATTCT
TTAAAATCCTGTCGGCATTAAATTTAGAACTTACGGTTACTCCCAGGAATATGGATGCCGCCAATAACGAGGCCTCTGTC
GCACCATCCTGGAAGGAAGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References