Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4378275..4378791 Replicon chromosome
Accession NZ_CP060595
Organism Pseudomonas monteilii strain A2

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2HKE7
Locus tag H9H53_RS20125 Protein ID WP_016712032.1
Coordinates 4378275..4378562 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A446A2J5
Locus tag H9H53_RS20130 Protein ID WP_028700126.1
Coordinates 4378552..4378791 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9H53_RS20115 4374335..4375288 + 954 WP_169725160.1 TniB family NTP-binding protein -
H9H53_RS20120 4375285..4377789 + 2505 WP_155737843.1 zinc ribbon domain-containing protein -
H9H53_RS20125 4378275..4378562 - 288 WP_016712032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9H53_RS20130 4378552..4378791 - 240 WP_028700126.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H9H53_RS20135 4379392..4380630 + 1239 WP_235200156.1 OprD family porin -
H9H53_RS20140 4380794..4381600 + 807 WP_235200157.1 NAD(P)-dependent oxidoreductase -
H9H53_RS20145 4381627..4382508 + 882 WP_235200158.1 SMP-30/gluconolactonase/LRE family protein -
H9H53_RS20150 4382574..4383545 + 972 WP_019098126.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4285141..4378791 93650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11233.07 Da        Isoelectric Point: 9.9006

>T170521 WP_016712032.1 NZ_CP060595:c4378562-4378275 [Pseudomonas monteilii]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

>T170521 NZ_CP077422:1654995-1655252 [Dickeya dadantii]
ATGCCTGAAATTGACAGACTGGCAGGGCTCATTTTCTATCTGTATTTTTACGATGATGGCAGGCACCACCAGCCTCATGT
GCATGTCTGTTACGGTGATGATGAGTTGATCATCGCGATAGATACAGGCATTGAGATCGAAGGCTATTTGCCCAATAGCA
AGCGTAAGATGGCGATTAGGCATATCAACGCGCATCGGCAACATTTGCTGGAAATGTGGAAACTGGCAGTGAAAGGCCGT
CATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9111.46 Da        Isoelectric Point: 4.6310

>AT170521 WP_028700126.1 NZ_CP060595:c4378791-4378552 [Pseudomonas monteilii]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL

Download         Length: 240 bp

>AT170521 NZ_CP077422:1655261-1655749 [Dickeya dadantii]
ATGCATAAAATCATCGATGTTGATGTGACTGGTGACTTTTCCTTGCGGCTGACCTATGAGGACGGCTTGATCTGTGATGT
CGATCTTTACCAATACGCCCCTGGTCCGGTGTTTTCGAACGCCAGCCTATTTATCAAGTTTGGCCTGTTGCCGGATGGCG
CGCTGGAATGGCTGCCGGATATTAAGATTTCCGCGTCAGACTTGCGGAAAAAAGGCGTGTATGTCGGCCACACGCTGGCG
GTGCGAGAAAGGCACTTCGCTGATGTTATCTCTCGCGCCTTCTATGACGCCGTGATTGAGAACCGGCCGGAAATTCTACA
GGCGGCGTTGAAAACCGCGGTGGAAAAACATGGCAACAGCACCGTAGCCAAAGAGGCGGGGGCGAAAAGCCGCACCAGCC
TGTATAAGTCGCTGAATAAGAATACCAACGTCAGTCTGGCGACGGTGGTCAGCCTGGCGCATACCGTGCTGCAACTGGAA
GAGAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HKE7

Antitoxin

Source ID Structure
AlphaFold DB A0A446A2J5

References