170520

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 282281..282887 Replicon chromosome
Accession NZ_CP060595
Organism Pseudomonas monteilii strain A2

Toxin (Protein)


Gene name PfiT Uniprot ID A0A0P7DAM5
Locus tag H9H53_RS01215 Protein ID WP_028699105.1
Coordinates 282281..282628 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A0P7CI78
Locus tag H9H53_RS01220 Protein ID WP_028699104.1
Coordinates 282639..282887 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9H53_RS01200 277714..279081 - 1368 WP_063977359.1 ATP-binding protein -
H9H53_RS01205 279083..279805 - 723 WP_235200312.1 response regulator -
H9H53_RS01210 279946..282243 + 2298 WP_028699106.1 TonB-dependent siderophore receptor -
H9H53_RS01215 282281..282628 - 348 WP_028699105.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9H53_RS01220 282639..282887 - 249 WP_028699104.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H9H53_RS01225 283715..284434 + 720 WP_235200313.1 hypothetical protein -
H9H53_RS01230 284554..285567 + 1014 WP_235200314.1 DUF3883 domain-containing protein -
H9H53_RS01235 286141..287028 + 888 WP_235200315.1 sce7726 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-100)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 116 a.a.        Molecular weight: 12823.64 Da        Isoelectric Point: 5.9608

>T170520 WP_028699105.1 NZ_CP060595:c282628-282281 [Pseudomonas monteilii]
MSNPSIRFTHSASQSIEDQVHHLAVYHGTAAALEKITTLVDTIEHRLAAAPVGYPVSPQASGLGVMQYRELNIEGYRVFY
EVIETDNAIAVELVLRQKQSVEQALIRYCLIYPLP

Download         Length: 348 bp

>T170520 NZ_CP077422:c1252716-1252513 [Dickeya dadantii]
ATGAAAAAAATCGACTATTTAATGCGTTTGCGTAAATGTACAACCATCGACACGCTTGAACGTGTTATAGAAAAAAACAA
GTACGAGCTTTCCAACGACGAGCTTGAAATGTTCTATTCAGCTGCAGACCACCGCCTGGCAGAGCTGACGATGAATAAAC
TTTACGACAAAGTACCGACTGCTGTGTGGAAATACGTTCGCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9277.58 Da        Isoelectric Point: 6.4706

>AT170520 WP_028699104.1 NZ_CP060595:c282887-282639 [Pseudomonas monteilii]
MRVETISYLKRHAADLDLEEPMVVTQNGVPAYVVESYADRKQRDEAIALVKLLAIGSREYAQGKHSSAEDLKARLLKKFS
EE

Download         Length: 249 bp

>AT170520 NZ_CP077422:c1253138-1252770 [Dickeya dadantii]
ATGGATGAGTACACACCTCAACATTATGATATTGCCCAACTCAGATTCTTGTGTGAAAATCTGCACGACGAAAGTATCGC
GACATTAGGTGACAGCAGTCGTGGCTGGGTGAATGATCCGACCTCTGCGGTCAACCTTCAACTAAACGAACTTATCGAAC
ATATTGCGGCATTTGTTGTTACCTACAAAATAAAATATCCGCATGAAGCGGCGTTATGTGAACGGGTTGAGAAATATCTG
GACGACACTTATATTCTTTTCAGCAATTACGGTATAAATGACACCGAGTTGCGGAAATGGCAAAAATCCAAGTCACAATT
ATTCAGAATGTTCTCAGAAAAGAGCATCTGTACGGTAGTAAAAACTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0P7DAM5


Antitoxin

Source ID Structure
AlphaFold DB A0A0P7CI78

References