Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PfiT-PfiA/ParE(toxin) |
Location | 282281..282887 | Replicon | chromosome |
Accession | NZ_CP060595 | ||
Organism | Pseudomonas monteilii strain A2 |
Toxin (Protein)
Gene name | PfiT | Uniprot ID | A0A0P7DAM5 |
Locus tag | H9H53_RS01215 | Protein ID | WP_028699105.1 |
Coordinates | 282281..282628 (-) | Length | 116 a.a. |
Antitoxin (Protein)
Gene name | PfiA | Uniprot ID | A0A0P7CI78 |
Locus tag | H9H53_RS01220 | Protein ID | WP_028699104.1 |
Coordinates | 282639..282887 (-) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
H9H53_RS01200 | 277714..279081 | - | 1368 | WP_063977359.1 | ATP-binding protein | - |
H9H53_RS01205 | 279083..279805 | - | 723 | WP_235200312.1 | response regulator | - |
H9H53_RS01210 | 279946..282243 | + | 2298 | WP_028699106.1 | TonB-dependent siderophore receptor | - |
H9H53_RS01215 | 282281..282628 | - | 348 | WP_028699105.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
H9H53_RS01220 | 282639..282887 | - | 249 | WP_028699104.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
H9H53_RS01225 | 283715..284434 | + | 720 | WP_235200313.1 | hypothetical protein | - |
H9H53_RS01230 | 284554..285567 | + | 1014 | WP_235200314.1 | DUF3883 domain-containing protein | - |
H9H53_RS01235 | 286141..287028 | + | 888 | WP_235200315.1 | sce7726 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 116 a.a. Molecular weight: 12823.64 Da Isoelectric Point: 5.9608
>T170520 WP_028699105.1 NZ_CP060595:c282628-282281 [Pseudomonas monteilii]
MSNPSIRFTHSASQSIEDQVHHLAVYHGTAAALEKITTLVDTIEHRLAAAPVGYPVSPQASGLGVMQYRELNIEGYRVFY
EVIETDNAIAVELVLRQKQSVEQALIRYCLIYPLP
MSNPSIRFTHSASQSIEDQVHHLAVYHGTAAALEKITTLVDTIEHRLAAAPVGYPVSPQASGLGVMQYRELNIEGYRVFY
EVIETDNAIAVELVLRQKQSVEQALIRYCLIYPLP
Download Length: 348 bp
>T170520 NZ_CP077422:c1252716-1252513 [Dickeya dadantii]
ATGAAAAAAATCGACTATTTAATGCGTTTGCGTAAATGTACAACCATCGACACGCTTGAACGTGTTATAGAAAAAAACAA
GTACGAGCTTTCCAACGACGAGCTTGAAATGTTCTATTCAGCTGCAGACCACCGCCTGGCAGAGCTGACGATGAATAAAC
TTTACGACAAAGTACCGACTGCTGTGTGGAAATACGTTCGCTAA
ATGAAAAAAATCGACTATTTAATGCGTTTGCGTAAATGTACAACCATCGACACGCTTGAACGTGTTATAGAAAAAAACAA
GTACGAGCTTTCCAACGACGAGCTTGAAATGTTCTATTCAGCTGCAGACCACCGCCTGGCAGAGCTGACGATGAATAAAC
TTTACGACAAAGTACCGACTGCTGTGTGGAAATACGTTCGCTAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9277.58 Da Isoelectric Point: 6.4706
>AT170520 WP_028699104.1 NZ_CP060595:c282887-282639 [Pseudomonas monteilii]
MRVETISYLKRHAADLDLEEPMVVTQNGVPAYVVESYADRKQRDEAIALVKLLAIGSREYAQGKHSSAEDLKARLLKKFS
EE
MRVETISYLKRHAADLDLEEPMVVTQNGVPAYVVESYADRKQRDEAIALVKLLAIGSREYAQGKHSSAEDLKARLLKKFS
EE
Download Length: 249 bp
>AT170520 NZ_CP077422:c1253138-1252770 [Dickeya dadantii]
ATGGATGAGTACACACCTCAACATTATGATATTGCCCAACTCAGATTCTTGTGTGAAAATCTGCACGACGAAAGTATCGC
GACATTAGGTGACAGCAGTCGTGGCTGGGTGAATGATCCGACCTCTGCGGTCAACCTTCAACTAAACGAACTTATCGAAC
ATATTGCGGCATTTGTTGTTACCTACAAAATAAAATATCCGCATGAAGCGGCGTTATGTGAACGGGTTGAGAAATATCTG
GACGACACTTATATTCTTTTCAGCAATTACGGTATAAATGACACCGAGTTGCGGAAATGGCAAAAATCCAAGTCACAATT
ATTCAGAATGTTCTCAGAAAAGAGCATCTGTACGGTAGTAAAAACTTAA
ATGGATGAGTACACACCTCAACATTATGATATTGCCCAACTCAGATTCTTGTGTGAAAATCTGCACGACGAAAGTATCGC
GACATTAGGTGACAGCAGTCGTGGCTGGGTGAATGATCCGACCTCTGCGGTCAACCTTCAACTAAACGAACTTATCGAAC
ATATTGCGGCATTTGTTGTTACCTACAAAATAAAATATCCGCATGAAGCGGCGTTATGTGAACGGGTTGAGAAATATCTG
GACGACACTTATATTCTTTTCAGCAATTACGGTATAAATGACACCGAGTTGCGGAAATGGCAAAAATCCAAGTCACAATT
ATTCAGAATGTTCTCAGAAAAGAGCATCTGTACGGTAGTAAAAACTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0P7DAM5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0P7CI78 |