Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 98249..98985 Replicon plasmid pUnnamed1
Accession NZ_CP060593
Organism Rouxiella badensis strain C173

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag H2866_RS23015 Protein ID WP_192504525.1
Coordinates 98506..98985 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag H2866_RS23010 Protein ID WP_192504524.1
Coordinates 98249..98509 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H2866_RS22985 93496..94203 - 708 WP_192504520.1 IS6 family transposase -
H2866_RS22990 94570..95400 + 831 WP_192504521.1 SDR family oxidoreductase -
H2866_RS22995 95431..96348 - 918 WP_192504522.1 LysR family transcriptional regulator -
H2866_RS23000 96515..97348 + 834 WP_192504523.1 SDR family oxidoreductase -
H2866_RS23005 97665..97868 - 204 Protein_105 IS3 family transposase -
H2866_RS23010 98249..98509 + 261 WP_192504524.1 DUF1778 domain-containing protein Antitoxin
H2866_RS23015 98506..98985 + 480 WP_192504525.1 GNAT family N-acetyltransferase Toxin
H2866_RS23020 99077..100126 - 1050 WP_192504526.1 tyrosine-type recombinase/integrase -
H2866_RS23025 100458..103817 - 3360 WP_192504527.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..120691 120691


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(26-147)

Antitoxin

Vibrio phage ICP1, Orf50

(6-80)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17388.98 Da        Isoelectric Point: 7.4734

>T170519 WP_192504525.1 NZ_CP060593:98506-98985 [Rouxiella badensis]
MSLQLSAPEPLTTEHILDDFGCGESTLDEWLKRRALTNHLNGASRTFVVATDDKSVVGYYALAAGAVTHREATGSVRRNM
PDPVPVIVLGRLAVDLRTQGLKLGASLLQDAVLRVRSIAENTGVRALLVHALHEPAKQFYEHYGFTSSPINPMTLMLRL

Download         Length: 480 bp

>T170519 NZ_CP077422:705296-705727 [Dickeya dadantii]
GTGGCCCAGTGGCAATGTGATTTGCGCGTATCCTGGCGCATGCAGCTGTTTTCGCTGCTGACGCACGGGTTTCTGGTGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGCTGGTGACGCTGGTGGTGTTCGGTTTTG
TGTTCAGCCAGCGCATCATCAAGACGCGTCAGGGGGAGATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGCAGCGT
GACTGGCAGATAGTCCGGCGGCCGTGGCTGATGCGCAACGGCGTGTTGCTGTCATTGCGGGCGGTGGATGGCAAAGGGCA
TCAACGCCTGTGGCTGGCGTCTGACAGTATGGGCAACGAAGAGTGGCGGCTGTTGCGCCAACTGCTGCAGCAGCATTCGC
TGCAGGGAACGGAATCCTCCCACCATCATTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9749.22 Da        Isoelectric Point: 4.5741

>AT170519 WP_192504524.1 NZ_CP060593:98249-98509 [Rouxiella badensis]
MRDAAINLRALPEQRDLIDQAASLLGKNRSDFMLEVACERAQAILLDQVFFQLDSKKFDEFTALLDAPQKANQGLERLME
VKAPWA

Download         Length: 261 bp

>AT170519 NZ_CP077422:705049-705315 [Dickeya dadantii]
ATGGACATCAATAACAAATCACGTATTCACTGGGCGTGCAGACGCGGAATGCGTGAGCTGGATATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCAGTTCATCCGTCTGTTACAGTGCGACGATCCCGACT
TGTTCAACTGGTTGATGAACCACGGCGAGCCGGTGGATCCGGCGCTGAAACGCATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References