Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2280871..2281398 Replicon chromosome
Accession NZ_CP060592
Organism Rouxiella badensis strain C173

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H2866_RS10560 Protein ID WP_192504368.1
Coordinates 2281123..2281398 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H2866_RS10555 Protein ID WP_192504367.1
Coordinates 2280871..2281119 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H2866_RS10525 2276921..2277562 - 642 WP_192504363.1 hypothetical protein -
H2866_RS10530 2277891..2278394 + 504 WP_192504439.1 hypothetical protein -
H2866_RS10535 2278663..2279091 + 429 WP_192504440.1 DNA repair protein RadC -
H2866_RS10540 2279105..2279440 + 336 WP_192504364.1 type IV toxin-antitoxin system YeeU family antitoxin -
H2866_RS10545 2279507..2279827 + 321 WP_192504365.1 TA system toxin CbtA family protein -
H2866_RS10550 2279941..2280774 + 834 WP_192504366.1 DUF4942 domain-containing protein -
H2866_RS10555 2280871..2281119 + 249 WP_192504367.1 ribbon-helix-helix domain-containing protein Antitoxin
H2866_RS10560 2281123..2281398 + 276 WP_192504368.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H2866_RS10565 2281695..2282183 - 489 Protein_2042 transposase family protein -
H2866_RS10570 2282180..2282296 - 117 WP_192504369.1 transposase -
H2866_RS10575 2282414..2283034 - 621 WP_192504370.1 hypothetical protein -
H2866_RS10580 2283293..2283370 + 78 WP_081601429.1 hypothetical protein -
H2866_RS10585 2283604..2283969 + 366 WP_165429822.1 integrase core domain-containing protein -
H2866_RS10590 2283884..2286277 + 2394 WP_192504371.1 family 20 glycosylhydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2271930..2283034 11104


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11106.43 Da        Isoelectric Point: 5.5782

>T170508 WP_192504368.1 NZ_CP060592:2281123-2281398 [Rouxiella badensis]
MEIQWTQKAQDDLERIYRFACQYSRQHADNVLERLIIGTSGLADHPRIGVPQTRYEPREVRKILFDDYDVHYEIQRDTIY
IVDLWHTREDR

Download         Length: 276 bp

>T170508 NZ_CP077421:849870-850286 [Pectobacterium polaris]
GTGAGTCGCTTGTTCATGCTGGATACCAATATCTGTTCCTTCATTATGCGTGAACACCCGACAGCGATGATTGACAAGCT
ACAGCAGTGCACATTGCGGCGTGATCGGATCGTGGTCTCTGCTATCACTTACGCTGAAATGCGTTTCGGGGCGGTTGGAA
AAAAAGCTTCGCCACGCCATATGCAACTAGTTGATGCTTTCTGTCGTCGGCTCGATGCGGTGTTACCTTGGGATAGCGCA
GCAGTAGACGCCACTACGAAAATCAAAATTGCGTTAGCCGCCGCAGGCACGCCTATTGGCCCAAATGATACGGCCATCGC
TGGTCATGCCATCAGCGTTAAGGCCATATTGGTTACCAATAACCTGAGAGAGTTTGAGCGAGTACAAGGACTAACGTTGG
AAGATTGGGTTAACTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9121.53 Da        Isoelectric Point: 8.7560

>AT170508 WP_192504367.1 NZ_CP060592:2280871-2281119 [Rouxiella badensis]
MRQLAKQTISAQIPAELAAAVENLAIELDRSKSWVIKEALTAMIEERERRHQQILKGLADVDAGRVVSHADVVDFANKLK
KS

Download         Length: 249 bp

>AT170508 NZ_CP077421:849646-849873 [Pectobacterium polaris]
ATGCGTATTGTTTCGGTATTTAAAAATGGTAACAACCGTGCCATTCGCTTGCCACGTGATATGGACTTTGAAGGGGTCAA
CGAACTGGAGATCGTGCGTGAGGGGGATACCATCATGCTGCGTCCGGTTAAACCCAATTGGCATTCATTTTTGCAAGAAG
AGCGCGCTGACGCTGACTTTATGACAGAACGTCAGGATGTAGTCGAAGAGGGGAGATTCGAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References