Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 978819..979533 Replicon chromosome
Accession NZ_CP060592
Organism Rouxiella badensis strain C173

Toxin (Protein)


Gene name cptA Uniprot ID A0A1X0WDA6
Locus tag H2866_RS04470 Protein ID WP_038328038.1
Coordinates 978819..979286 (-) Length 156 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1X0WD57
Locus tag H2866_RS04475 Protein ID WP_017492114.1
Coordinates 979267..979533 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H2866_RS04450 974711..976444 - 1734 WP_192504116.1 single-stranded-DNA-specific exonuclease RecJ -
H2866_RS04455 976507..977214 - 708 WP_017492110.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
H2866_RS04460 977241..978122 - 882 WP_038328043.1 site-specific tyrosine recombinase XerD -
H2866_RS04465 978279..978797 + 519 WP_017492112.1 flavodoxin FldB -
H2866_RS04470 978819..979286 - 468 WP_038328038.1 protein YgfX Toxin
H2866_RS04475 979267..979533 - 267 WP_017492114.1 FAD assembly factor SdhE Antitoxin
H2866_RS04480 979811..980803 + 993 WP_017491354.1 tRNA-modifying protein YgfZ -
H2866_RS04485 980915..983344 - 2430 WP_192504117.1 M60 family metallopeptidase -
H2866_RS04490 983560..984207 - 648 WP_192504118.1 hemolysin III family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-140)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 18280.52 Da        Isoelectric Point: 11.7962

>T170506 WP_038328038.1 NZ_CP060592:c979286-978819 [Rouxiella badensis]
VALWQCDLRVSWRSQLFSLAVHGILILLILLAPWPPDDWMIWLILLIIVVSQSIRSQRRISARQGEISLLAQDRLLWRKQ
EWKIKQPVWMIDSGILLSLRRERTGHGWRQALRGKKHKLWLASDSMSQEEWRHLRQILLTGKRDAAPANNNHHPL

Download         Length: 468 bp

>T170506 NZ_CP077421:150175-150657 [Pectobacterium polaris]
ATGGGAATAACTGCACCAGAGCCATTATCCTCCGGCCATAATCTTGCTGAATTTTGCAGCCAAGAACCGAGTTTGAATGA
ATGGCTAAAAAAGAAAGCGCTAAAAAATCATAGTGCAGGGATCTCCCGCGTATATGTTATTTGCGCTGAAGGCACGCATC
AGGTGATTGGATATTATTGTTTATCAACAGGTAGCGTTCAGAGAAATACAGCGCCTGGTGCATATAGGCGTAATGCCCCC
GAATCACTACCAGTCATTGTCCTTGGGCGACTTGCCATTGATCAGGCGTATTCTGGTAAAGGTTTGGGTGTGGCTTTATT
AAAAGACGCGATATTTCGGACTGAGAATATTGCTTTGCAAGTGGGTGTGAGGGCATTAGTCGTTCACGCTCTGGATGAGA
ACGTGCGCAATTTCTATCTTAAATTCGCTTTTGATCCCTCGCCAGTGCAGCCTCTGATGCTACTCTATCCAATTAAAATT
TAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10563.10 Da        Isoelectric Point: 4.6436

>AT170506 WP_017492114.1 NZ_CP060592:c979533-979267 [Rouxiella badensis]
MDINNKPRIHWACRRGMKELDLAILPFFEYEFDTLSDEDKQQFARLLECDDPDLFNWLMNYGEPNDLELKRMVNLIQTRN
KQRGPVAM

Download         Length: 267 bp

>AT170506 NZ_CP077421:149906-150184 [Pectobacterium polaris]
ATGAAACCTGAAACTAAAGAAGCGCCAATCAATATTCGGGCCAAAGCCTCCCAACGGGACTTGATCGATATGGCTGCAAA
CCTTGTGTCAAAATCACGTACCGATTTTATGCTTGAAGCCGCCTGTCGCGAGGCGCAGGACATCTTGTTGGATCAACGTT
TGTTTATTTTGGACAACGAACAGTTTGACGAATTTTTGGCCGAGTTGGATGCACCTATCACCGCAGAGCGTCAGGCTCGC
ATTAACGATCTGATGAGCCGTAAATCTCCATGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X0WDA6

Antitoxin

Source ID Structure
AlphaFold DB A0A1X0WD57

References