Detailed information of TA system TA170482

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 55688..56210
• Replicon: plasmid pS7627-2
• Accession: NZ_CP060519
• Organism: Salmonella enterica strain SLR1_7627

Toxin (Protein)

• Gene name: relE
• Uniprot ID: U9YLU1
• Locus tag: H9L30_RS24375
• Protein ID: WP_000638823.1
• Coordinates: 55688..55969 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: U9Y7J1
• Locus tag: H9L30_RS24380
• Protein ID: WP_000121741.1
• Coordinates: 55959..56210 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H9L30_RS24340	51837..52157	-	321	WP_000362080.1	VirB3 family type IV secretion system protein	-
H9L30_RS24345	52228..52416	-	189	WP_050567133.1	hypothetical protein	-
H9L30_RS24350	52518..53102	-	585	WP_001177113.1	lytic transglycosylase domain-containing protein	-
H9L30_RS24355	53123..53521	-	399	WP_001153665.1	hypothetical protein	-
H9L30_RS24360	53640..54077	-	438	WP_000539665.1	type IV pilus biogenesis protein PilM	-
H9L30_RS24365	54083..55318	-	1236	WP_015059538.1	TcpQ domain-containing protein	-
H9L30_RS24370	55321..55620	-	300	WP_000835764.1	IncN plasmid KikA protein	-
H9L30_RS24375	55688..55969	-	282	WP_000638823.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H9L30_RS24380	55959..56210	-	252	WP_000121741.1	hypothetical protein	Antitoxin
H9L30_RS24385	56310..56945	-	636	WP_015059536.1	hypothetical protein	-
H9L30_RS24390	57018..57305	-	288	WP_001032611.1	EexN family lipoprotein	-
H9L30_RS24395	57318..57572	-	255	WP_001043555.1	EexN family lipoprotein	-
H9L30_RS24400	57574..58215	-	642	WP_001425343.1	conjugal transfer protein TrbJ	-
H9L30_RS24405	58221..59216	-	996	WP_001028543.1	type IV secretion system protein	-
H9L30_RS24410	59220..59477	-	258	WP_000739144.1	hypothetical protein	-
H9L30_RS24415	59474..59776	-	303	WP_001360345.1	hypothetical protein	-
H9L30_RS24420	59757..60014	-	258	WP_001542015.1	hypothetical protein	-
H9L30_RS24425	60047..60493	-	447	WP_001243165.1	hypothetical protein	-
H9L30_RS24430	60504..60674	-	171	WP_000550720.1	hypothetical protein	-
H9L30_RS24435	60678..61121	-	444	WP_000964330.1	NfeD family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..64443	64443

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 13852.62 Da
• Isoelectric Point: 5.5500

>T170482 WP_000638823.1 NZ_CP060519:c55969-55688 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Nucleotide

• Length: 282 bp

>T170482 NZ_CP077407:c1252549-1252446 [Enterobacter roggenkampii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 12380.85 Da
• Isoelectric Point: 5.5500

>AT170482 WP_000121741.1 NZ_CP060519:c56210-55959 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Nucleotide

• Length: 252 bp

>AT170482 NZ_CP077407:1252439-1252584 [Enterobacter roggenkampii]
AACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures

Toxin

• AlphaFold DB: U9YLU1

Antitoxin

• AlphaFold DB: U9Y7J1