Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 5154617..5155284 | Replicon | chromosome |
| Accession | NZ_CP060470 | ||
| Organism | Xanthomonas citri pv. citri strain DAR73889 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | M4U0C6 |
| Locus tag | H8Z72_RS22175 | Protein ID | WP_005916679.1 |
| Coordinates | 5154868..5155284 (+) | Length | 139 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | M4U000 |
| Locus tag | H8Z72_RS22170 | Protein ID | WP_005916676.1 |
| Coordinates | 5154617..5154871 (+) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H8Z72_RS22145 | 5150727..5150946 | + | 220 | Protein_4329 | RNA 2'-phosphotransferase | - |
| H8Z72_RS22150 | 5151115..5152380 | + | 1266 | WP_040280600.1 | cardiolipin synthase B | - |
| H8Z72_RS22155 | 5152406..5152933 | - | 528 | WP_005916668.1 | hypothetical protein | - |
| H8Z72_RS22160 | 5153172..5153378 | + | 207 | WP_003489327.1 | hypothetical protein | - |
| H8Z72_RS22165 | 5153365..5154471 | + | 1107 | WP_005916674.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H8Z72_RS22170 | 5154617..5154871 | + | 255 | WP_005916676.1 | Arc family DNA-binding protein | Antitoxin |
| H8Z72_RS22175 | 5154868..5155284 | + | 417 | WP_005916679.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| H8Z72_RS22180 | 5155406..5155618 | - | 213 | WP_015472900.1 | hypothetical protein | - |
| H8Z72_RS22185 | 5155737..5155949 | - | 213 | WP_203197330.1 | hypothetical protein | - |
| H8Z72_RS22190 | 5156206..5157825 | + | 1620 | WP_015463800.1 | hypothetical protein | - |
| H8Z72_RS22195 | 5157929..5158327 | - | 399 | WP_004429277.1 | DUF2384 domain-containing protein | - |
| H8Z72_RS22200 | 5158643..5159074 | + | 432 | WP_005922907.1 | hypothetical protein | - |
| H8Z72_RS22205 | 5159103..5159429 | - | 327 | Protein_4341 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 14795.09 Da Isoelectric Point: 5.6920
>T170451 WP_005916679.1 NZ_CP060470:5154868-5155284 [Xanthomonas citri pv. citri]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS
Download Length: 417 bp
>T170451 NZ_CP077388:2918016-2918753 [Providencia rettgeri]
GTGACTTTATTCGCTCAAGTACTGGGGCTCATCAGTTTAAATGATGTGCCCCATAGTTTTATTTTAAATGTAGGTGAAAT
AAAGGCGTTAGCGGTTGAACGTTTTGAGCGTAAATATTCTTCTGATTCCTCGTGGATTATGCGTTTACCACAAGAAGATT
TTTGTCAAACATTGAATATTTCACCGGCAAGAAAATATCAAAATCATGGTGGACCGGGTATTTCTGAAATTATGAATTAC
TTATTAGGTTCAATAAATGCAGAGAAAGATAGATATCAGTTTATGAAGAGCCAGGTTTTGTTTTGGTTACTTGCAGCGAC
GGATGGCCATGCTAAAAATTTTTCATTATTTATTGAACCTGAAGGCCGTTATCAGTTAACACCTTTTTACGATATTTTGT
CCATGTATCCTAGTTATGGGGGGAGGGGAATTAACCCTAGAGATGCCAAATTGGCTATGGGGCTGAAGGGAACAAGGGAG
ATGAAATACAATATAGAGCAAATTTTTCCAAGGCATTTTTTTGCAACGGCCAAGGAGGTTGGTTTTGACCGCACTGAAAT
GGAAAAAATCTTAATTGAGTTTGATGAGCAAATGGAAAGTGTTATTACAAAGGTTAGGGAACAGCTTCCAACCAATTTCC
CTAAGCACATTGCAGACTCAATTTTATCAGGGTTACATCATAAAGCCGCACGATTAAAAAAAGTTGGGATTAATCCTTTA
CCCGACTCGGATGGGTAA
GTGACTTTATTCGCTCAAGTACTGGGGCTCATCAGTTTAAATGATGTGCCCCATAGTTTTATTTTAAATGTAGGTGAAAT
AAAGGCGTTAGCGGTTGAACGTTTTGAGCGTAAATATTCTTCTGATTCCTCGTGGATTATGCGTTTACCACAAGAAGATT
TTTGTCAAACATTGAATATTTCACCGGCAAGAAAATATCAAAATCATGGTGGACCGGGTATTTCTGAAATTATGAATTAC
TTATTAGGTTCAATAAATGCAGAGAAAGATAGATATCAGTTTATGAAGAGCCAGGTTTTGTTTTGGTTACTTGCAGCGAC
GGATGGCCATGCTAAAAATTTTTCATTATTTATTGAACCTGAAGGCCGTTATCAGTTAACACCTTTTTACGATATTTTGT
CCATGTATCCTAGTTATGGGGGGAGGGGAATTAACCCTAGAGATGCCAAATTGGCTATGGGGCTGAAGGGAACAAGGGAG
ATGAAATACAATATAGAGCAAATTTTTCCAAGGCATTTTTTTGCAACGGCCAAGGAGGTTGGTTTTGACCGCACTGAAAT
GGAAAAAATCTTAATTGAGTTTGATGAGCAAATGGAAAGTGTTATTACAAAGGTTAGGGAACAGCTTCCAACCAATTTCC
CTAAGCACATTGCAGACTCAATTTTATCAGGGTTACATCATAAAGCCGCACGATTAAAAAAAGTTGGGATTAATCCTTTA
CCCGACTCGGATGGGTAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 8996.53 Da Isoelectric Point: 11.3362
>AT170451 WP_005916676.1 NZ_CP060470:5154617-5154871 [Xanthomonas citri pv. citri]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK
Download Length: 255 bp
>AT170451 NZ_CP077388:2917707-2917976 [Providencia rettgeri]
ATGAAAGTGACCAATACCCGACAACTTAGTGCTTACATGAAAGATGTCAGAGAGACGAAAAAATTATCTCAAAGTAAAGT
CGCAAGTAAAGTGGGTATTCGGCAAGATACCGTCTCCAGTTTTGAACTCTCTCCTGACTCTACCAAATTAGAAACCTTCT
TTAAGATTTTATCTGCCCTAAATTTAGAACTCGATATTAAACCGCGAAATGAAAGTGGCTCATCAAACTCAAACTCAAAT
TCAAACTCTGGATGGAAGGAGGAGTGGTGA
ATGAAAGTGACCAATACCCGACAACTTAGTGCTTACATGAAAGATGTCAGAGAGACGAAAAAATTATCTCAAAGTAAAGT
CGCAAGTAAAGTGGGTATTCGGCAAGATACCGTCTCCAGTTTTGAACTCTCTCCTGACTCTACCAAATTAGAAACCTTCT
TTAAGATTTTATCTGCCCTAAATTTAGAACTCGATATTAAACCGCGAAATGAAAGTGGCTCATCAAACTCAAACTCAAAT
TCAAACTCTGGATGGAAGGAGGAGTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | M4U0C6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A828YKJ0 |