170440

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 320694..321055 Replicon chromosome
Accession NZ_CP060465
Organism Xanthomonas citri pv. citri strain DAR73886

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag H8Z71_RS01310 Protein ID WP_005914328.1
Coordinates 320921..321055 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag H8Z71_RS01305 Protein ID WP_003486606.1
Coordinates 320694..320846 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8Z71_RS01275 315794..316477 - 684 WP_011052674.1 dTMP kinase -
H8Z71_RS01280 316915..317457 - 543 WP_003486615.1 GTPase -
H8Z71_RS01285 317454..318371 - 918 WP_011052673.1 hypothetical protein -
H8Z71_RS01290 318468..318827 - 360 WP_003486613.1 hypothetical protein -
H8Z71_RS01295 318891..319343 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
H8Z71_RS01300 319664..320587 + 924 WP_005927745.1 arginase -
H8Z71_RS01305 320694..320846 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
H8Z71_RS01310 320921..321055 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
H8Z71_RS01315 321282..321491 + 210 WP_003486601.1 CsbD family protein -
H8Z71_RS01320 321672..322961 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
H8Z71_RS01325 323000..324034 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
H8Z71_RS01330 324226..325917 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T170440 WP_005914328.1 NZ_CP060465:320921-321055 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T170440 NZ_CP077373:c5973-5653 [Acinetobacter lwoffii]
ATGTTATTCATTGAAACCAGTATTTTTACCAAGCAAATCAAAGAACTTGTGAGTGATAAAGAGTATCGTCAGCTCCAGCA
AGATCTCTTGGTACAGCCTGATAAGGGCGACTTAATCAAGAATGGCGGAGGTATTCGTAAAGTACGTTGTGCTCAAGGTA
ACAAGGGTAAAAGTGGCGGTATCCGTGTGATCTACTATTGGGTCACAGAAGATGATCAGATCTTTTTCTTGGTAGCTTAT
CCAAAGTCTGTGAAAGACAATCTGACTGATAAAGAGACCTCGATCCTGCGTCAATTAGTGAAGGAGCAATTTCATGGATA
A

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT170440 WP_003486606.1 NZ_CP060465:320694-320846 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT170440 NZ_CP077373:c5660-5388 [Acinetobacter lwoffii]
ATGGATAACAGCTTATTTGATGACCTGGTTGCTTCAATTAAAGAAGCTGGTGCTATCAAACGTAATGAGATAAAGGCAAG
TCGAGTCACAGAGCTTGAATTGCCGGATATTAAGGAAGTACGTGAGAAAACTGGCTTAACCCAGGCAGAATTTGCTGCAC
GTTTGCATATCAGCGCGAGAACCCTGCAAAACTGGGAGCAAGGTCGTCGCTATCCGACTGGCCCTGCAGCGACTCTAATT
CGCATTCTGGATGCCCATCCAACCCTAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References