170433

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 321825..322186 Replicon chromosome
Accession NZ_CP060460
Organism Xanthomonas citri pv. citri strain DAR84832

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag H8Z70_RS01320 Protein ID WP_005914328.1
Coordinates 322052..322186 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag H8Z70_RS01315 Protein ID WP_003486606.1
Coordinates 321825..321977 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8Z70_RS01285 316925..317608 - 684 WP_011052674.1 dTMP kinase -
H8Z70_RS01290 318046..318588 - 543 WP_003486615.1 GTPase -
H8Z70_RS01295 318585..319502 - 918 WP_011052673.1 hypothetical protein -
H8Z70_RS01300 319599..319958 - 360 WP_003486613.1 hypothetical protein -
H8Z70_RS01305 320022..320474 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
H8Z70_RS01310 320795..321718 + 924 WP_005927745.1 arginase -
H8Z70_RS01315 321825..321977 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
H8Z70_RS01320 322052..322186 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
H8Z70_RS01325 322413..322622 + 210 WP_003486601.1 CsbD family protein -
H8Z70_RS01330 322803..324092 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
H8Z70_RS01335 324131..325165 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
H8Z70_RS01340 325357..327048 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T170433 WP_005914328.1 NZ_CP060460:322052-322186 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T170433 NZ_CP077367:103201-103488 [Pantoea agglomerans]
GTGAGTTATACCGTCAAATTCAGGGAAGAGGCTTTTAAAGAGTGGCAGAAGCTGGACAAATCTCTCCAGCAGCAGTTTGC
CAAAAAACTGAAGAAATGTTGTGATAATCCCCATATTCCTTCTGCCAGACTACGTGGGATTAAAGACTGCTATAAAATCA
AACTCAGAGCGTCCGGGTTTCGCCTGGTTTATCAGGTAATAGACGACCAGCTGGTGATTGCCGTTGTTGCTGTGGGTAAA
CGCGAGCGCAGCGATGTTTATCATCTTGCCAGTGAAAGGATGCGGTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT170433 WP_003486606.1 NZ_CP060460:321825-321977 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT170433 NZ_CP077367:102953-103204 [Pantoea agglomerans]
ATGCCAAACATTATTTTAAGCGATACCAGTGCCAGCGTAAGCGAACTGAAGAAAAACCCGATGGCCACGGTTAGTGCAGG
TGACGGTTATCCTGTCGCCATTCTTAACCGCAACCAGCCTGCATTCTATTGCGTCCCGGCTGAGCTTTATGAACAAATGC
TTGATGCCCTTGACGATCAGGAACTGGTTAAGCTGGTCAGTGAACGCAGCGGCCAGCGTCTGCTTGATGTCGATTTGGAT
GCGCTTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References