Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2331780..2331920 Replicon chromosome
Accession NZ_CP060440
Organism Serratia marcescens strain M158-1-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2331780..2331876 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2331780..2331920 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3V66_RS11160 2327070..2327906 + 837 WP_240024252.1 aminoglycoside phosphotransferase family protein -
H3V66_RS11165 2327946..2328296 - 351 WP_004940949.1 DUF4377 domain-containing protein -
H3V66_RS11170 2328432..2328839 - 408 WP_126178904.1 hypothetical protein -
H3V66_RS11175 2329907..2330716 + 810 WP_126193023.1 hypothetical protein -
H3V66_RS11180 2330927..2331061 - 135 WP_240024253.1 DUF1367 family protein -
H3V66_RS11185 2331127..2331702 + 576 Protein_2201 tyrosine-type recombinase/integrase -
- 2331780..2331876 - 97 - - Toxin
- 2331780..2331920 + 141 - - Antitoxin
H3V66_RS11190 2332018..2332359 - 342 WP_025302452.1 YebY family protein -
H3V66_RS11195 2332429..2333310 - 882 WP_060440195.1 copper homeostasis membrane protein CopD -
H3V66_RS11200 2333313..2333696 - 384 WP_004940886.1 CopC domain-containing protein YobA -
H3V66_RS11205 2334021..2334539 - 519 WP_038875847.1 non-heme ferritin -
H3V66_RS11210 2334884..2335114 + 231 WP_033638067.1 DNA polymerase III subunit theta -
H3V66_RS11215 2335148..2336101 - 954 WP_126180338.1 prolyl aminopeptidase -
H3V66_RS11220 2336296..2336721 - 426 WP_033653830.1 RNA polymerase-binding protein DksA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T170383 NZ_CP060440:c2331876-2331780 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT170383 NZ_CP060440:2331780-2331920 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References