Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1969381..1969526 Replicon chromosome
Accession NZ_CP060421
Organism Klebsiella pneumoniae strain BA2105

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1969417..1969519 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1969381..1969526 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBJ34_RS09895 1964511..1966571 + 2061 WP_064144834.1 oligopeptidase B -
HBJ34_RS09900 1966575..1967234 - 660 WP_002911407.1 exodeoxyribonuclease X -
HBJ34_RS09905 1967313..1967543 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HBJ34_RS09910 1967656..1968030 + 375 WP_014343244.1 CopC domain-containing protein YobA -
HBJ34_RS09915 1968034..1968903 + 870 WP_014343243.1 copper homeostasis membrane protein CopD -
HBJ34_RS09920 1968920..1969258 + 339 WP_002911404.1 YebY family protein -
- 1969381..1969526 - 146 - - Antitoxin
- 1969417..1969519 + 103 - - Toxin
HBJ34_RS09925 1969894..1970037 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HBJ34_RS09930 1970142..1971110 - 969 WP_074181864.1 VirK/YbjX family protein -
HBJ34_RS09935 1971267..1971920 + 654 WP_064144836.1 protein-serine/threonine phosphatase -
HBJ34_RS09940 1971917..1972108 - 192 WP_002911395.1 YebW family protein -
HBJ34_RS09945 1972206..1972445 - 240 WP_002911393.1 YebV family protein -
HBJ34_RS09950 1972561..1973994 - 1434 WP_064144837.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T170357 NZ_CP060421:1969417-1969519 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT170357 NZ_CP060421:c1969526-1969381 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References