Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 4255577..4256082 Replicon chromosome
Accession NZ_CP060401
Organism Xenorhabdus nematophila strain SII

Toxin (Protein)


Gene name relB Uniprot ID D3VB03
Locus tag H8F46_RS19170 Protein ID WP_013185277.1
Coordinates 4255577..4255831 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag H8F46_RS19175 Protein ID WP_041976483.1
Coordinates 4255828..4256082 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8F46_RS19150 4251370..4252368 + 999 WP_013185281.1 ketoacyl-ACP synthase III -
H8F46_RS19155 4252365..4253384 + 1020 WP_013185280.1 NAD(P)-dependent oxidoreductase -
H8F46_RS19160 4253377..4254183 + 807 WP_013185279.1 MBL fold metallo-hydrolase -
H8F46_RS19165 4254180..4255457 + 1278 WP_013185278.1 coenzyme F390 synthetase -
H8F46_RS19170 4255577..4255831 - 255 WP_013185277.1 Txe/YoeB family addiction module toxin Toxin
H8F46_RS19175 4255828..4256082 - 255 WP_041976483.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
H8F46_RS19180 4256226..4256996 - 771 WP_010846253.1 Fe(3+) dicitrate ABC transporter ATP-binding protein FecE -
H8F46_RS19185 4256997..4257953 - 957 WP_010846252.1 Fe(3+) dicitrate ABC transporter permease subunit FecD -
H8F46_RS19190 4257950..4258948 - 999 WP_013185273.1 iron-dicitrate ABC transporter permease FecC -
H8F46_RS19195 4258945..4259847 - 903 WP_113935488.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10245.67 Da        Isoelectric Point: 8.8345

>T170340 WP_013185277.1 NZ_CP060401:c4255831-4255577 [Xenorhabdus nematophila]
MILSWAETAWEDYLYWQQTDKKTLKRINTLIKDIARQSFDGLGDPEPLKHNWSGYWSRRIDREHRLVYKVTDTAIIIVQC
RYHY

Download         Length: 255 bp

>T170340 NZ_CP077291:c2330410-2330132 [Citrobacter farmeri]
ATGATCATGAATTTCAGACATAAAGGATTACGTGACCTGTTTCTTCACGGCAAAACGTCAGGTGTGATGGCAAAGCACGT
CAGACGTTTACGACACCGCCTTGCTGTGATTGATGCCGCTGGCTGCGTGAACGATATCAATATGCCCGGTTACCGACTGC
ATCCCCTGAGCGGCGATCGCGATGGCGTCTGGGCAATTTCGGTTTCAGGCAACTGGCGTTTGACGTTTGAATTCGTCAAT
GGCGATGCGTACATTCTGGATTACGAGGATTATCACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9481.75 Da        Isoelectric Point: 5.0893

>AT170340 WP_041976483.1 NZ_CP060401:c4256082-4255828 [Xenorhabdus nematophila]
MNVMSYSAFRTHLAKTLDKVNDDHQPVMITRQNGKPAVVLSLEDFRAYEETAYLMASPKNAARLNQAIAEVENGKTLEKD
LLEE

Download         Length: 255 bp

>AT170340 NZ_CP077291:c2330132-2329848 [Citrobacter farmeri]
ATGAAAATGGCGAATCATCCCCGCCCCGGGGACATCATTCAGGAAGCGCTGGACGAACTAAACGTTAGTTTGCGTGAATT
TGCCAGGGCAATGGAGATTGCGCCCTCAACGGCAAGTCGGTTACTCACGGGCAAAGCGGCCCTCACCCCAGAGATGGCGA
TCAAACTCTCGGTGGTGATCGGCAGTTCTCCGGAAATGTGGCTGAATCTGCAAAATACCTGGAGTCTGGCAGAAGCGCAA
AAAAGCGTTGACGTTTCCCGCCTGCGCCGACTGGCCGTTCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D3VB03

Antitoxin

Source ID Structure

References