170320

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4775941..4776306 Replicon chromosome
Accession NZ_CP060399
Organism Xanthomonas hortorum pv. vitians strain LM16734

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6V7C9X4
Locus tag XHV734_RS20605 Protein ID WP_074056472.1
Coordinates 4775941..4776075 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag XHV734_RS20610 Protein ID WP_006451340.1
Coordinates 4776154..4776306 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XHV734_RS20590 4772875..4773819 - 945 WP_095575004.1 MBL fold metallo-hydrolase -
XHV734_RS20595 4774027..4775316 - 1290 WP_074056473.1 tryptophan--tRNA ligase -
XHV734_RS20600 4775490..4775699 - 210 WP_006451342.1 CsbD family protein -
XHV734_RS20605 4775941..4776075 - 135 WP_074056472.1 entericidin A/B family lipoprotein Toxin
XHV734_RS20610 4776154..4776306 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
XHV734_RS20615 4776416..4777339 - 924 WP_095575354.1 arginase -
XHV734_RS20620 4777801..4778253 + 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
XHV734_RS20625 4778317..4778676 + 360 WP_006452081.1 hypothetical protein -
XHV734_RS20630 4778770..4779687 + 918 WP_074056471.1 hypothetical protein -
XHV734_RS20635 4779684..4780226 + 543 WP_180313759.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.31 Da        Isoelectric Point: 9.3487

>T170320 WP_074056472.1 NZ_CP060399:c4776075-4775941 [Xanthomonas hortorum pv. vitians]
MKRAIILLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T170320 NZ_CP077279:c3326995-3326893 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT170320 WP_006451340.1 NZ_CP060399:c4776306-4776154 [Xanthomonas hortorum pv. vitians]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT170320 NZ_CP077279:3326889-3327036 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7C9X4

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References