Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3831414..3831919 Replicon chromosome
Accession NZ_CP060399
Organism Xanthomonas hortorum pv. vitians strain LM16734

Toxin (Protein)


Gene name relE Uniprot ID A0A6V7D3A5
Locus tag XHV734_RS16115 Protein ID WP_074056859.1
Coordinates 3831662..3831919 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag XHV734_RS16110 Protein ID WP_006448404.1
Coordinates 3831414..3831665 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XHV734_RS16090 3826785..3827939 - 1155 WP_074056862.1 2-methylcitrate synthase -
XHV734_RS16095 3828015..3828911 - 897 WP_074056861.1 methylisocitrate lyase -
XHV734_RS16100 3829040..3830659 + 1620 WP_174555969.1 propionate catabolism operon regulatory protein PrpR -
XHV734_RS16105 3830902..3831228 - 327 WP_074056860.1 hypothetical protein -
XHV734_RS16110 3831414..3831665 + 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
XHV734_RS16115 3831662..3831919 + 258 WP_074056859.1 Txe/YoeB family addiction module toxin Toxin
XHV734_RS16125 3832434..3832787 - 354 WP_003483889.1 PilZ domain-containing protein -
XHV734_RS16130 3832784..3833743 - 960 WP_006448409.1 DNA polymerase III subunit delta' -
XHV734_RS16135 3833740..3834849 - 1110 WP_074056858.1 endolytic transglycosylase MltG -
XHV734_RS16140 3834865..3836220 - 1356 WP_074056857.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.66 Da        Isoelectric Point: 9.6587

>T170319 WP_074056859.1 NZ_CP060399:3831662-3831919 [Xanthomonas hortorum pv. vitians]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYG

Download         Length: 258 bp

>T170319 NZ_CP077279:2646334-2647656 [Klebsiella quasipneumoniae]
ATGGCGACGCTCACCACCTGGATGAACAATGCGCGCGTGGGAACCTTAACCCGCCAGGCCAACGGGGCGCACAGTTTCCG
CTATGATGAGGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATTACCG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGAGCGGATCGTCAGGCGCTATCAG
GCGCGTTCGAAACAGCCGTTCGATCTGCTGGCCGAGGTCGGGCGGGACAGCGTAGGGGCGGTGACTCTGCTGCCGCCGGG
GGAAGAGGCGCATCTTGCCGCGTTGCGCTGGCAGACGCTGGATGAGGCGCAGCTGACCGCTTTGCTGACCGCCTACCAGT
CGGATATTCCTCTCGGAATGGTGACCGGCCAGGACGATTTTCGTATCTCGGTGGCCGGCGCTCAGGAGAAAACCGCGCTG
CTGCGAATGGGCGAGCACTGGTGTATTCCGCAGGGCACCACCCCGACCACCCATATCATTAAACTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAATATCTGTGCCTGGCGCTGGCCAGGGCGTTGG
GCCTGGCGGTGCCGGAGGCGGAGATTATCAACACGCCGCGGATCCGTGCGCTGGCGGTGACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGGCGCGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCATTCGGCATACCGTCGTCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCCAGTGAGGCCCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTGTTCCAGTGGCTGACCGGGGCAACGGACGGGCATGCGAAGAACTTCTCGCTCTTTTTGCTG
CCCGGCGGCAGCTACCGGCTCACGCCGTTCTACGACATTATTTCGGCATTTCCGGTGCTGGGCGGGACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGGAAAACGGAGATTAACGCTATCTATCCGCGTCATT
TTCTGGCGACCGCCAAAGCGGTTAACTTCCCCCGGGAGCAGATGCTGGCGATCCTGGGCGAGTTTGCCGACCGCGTGCCG
CAGGCCATCGAAAGCGCCCGCCAAACGCTGCCGTCGGACTTTTCCGCCCACGTCTGGCGGGCCATCACGGAGAACATGCT
GAAACTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGGGATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT170319 WP_006448404.1 NZ_CP060399:3831414-3831665 [Xanthomonas hortorum pv. vitians]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp

>AT170319 NZ_CP077279:2646068-2646334 [Klebsiella quasipneumoniae]
ATGAATTCCCCGCAGATATACAGTCCGGTTCAGCTGGCCAATTACCTGAAACTGCTGCGCCAGCAAAATCACTGGACTCA
GGAGGCGCTGGCCAGCCGGATCGGCATTAAACAGGCGACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACCCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACCCTGAACGCCAAACCGGCAGAGACGGCGATGATTCCC
GATAACACCACGGATCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7D3A5

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References