Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1501342..1501867 Replicon chromosome
Accession NZ_CP060398
Organism Synechococcus sp. CBW1002

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H8F24_RS07110 Protein ID WP_197171564.1
Coordinates 1501342..1501623 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H8F24_RS07115 Protein ID WP_197157429.1
Coordinates 1501613..1501867 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8F24_RS07080 1496481..1497059 - 579 WP_197171562.1 hypothetical protein -
H8F24_RS07085 1497078..1497359 - 282 WP_197157419.1 type II toxin-antitoxin system RelE/ParE family toxin -
H8F24_RS07090 1497349..1497603 - 255 WP_197157421.1 hypothetical protein -
H8F24_RS07095 1498203..1500530 - 2328 WP_197172087.1 DEAD/DEAH box helicase -
H8F24_RS07100 1500601..1500948 - 348 WP_197157423.1 type II toxin-antitoxin system PemK/MazF family toxin -
H8F24_RS07105 1500948..1501265 - 318 WP_197157425.1 ribbon-helix-helix protein, CopG family -
H8F24_RS07110 1501342..1501623 - 282 WP_197171564.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H8F24_RS07115 1501613..1501867 - 255 WP_197157429.1 plasmid stabilization protein Antitoxin
H8F24_RS07120 1502223..1504589 - 2367 WP_197172090.1 DEAD/DEAH box helicase -
H8F24_RS07125 1504658..1504849 - 192 WP_197157431.1 type II toxin-antitoxin system RelE/ParE family toxin -
H8F24_RS07130 1505150..1505485 + 336 WP_197157433.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
H8F24_RS07135 1505499..1505861 + 363 WP_197157435.1 type II toxin-antitoxin system VapC family toxin -
H8F24_RS07140 1506024..1506434 + 411 WP_197157437.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.72 Da        Isoelectric Point: 11.0535

>T170315 WP_197171564.1 NZ_CP060398:c1501623-1501342 [Synechococcus sp. CBW1002]
MLFELAFHPEALREWRKLTPGIREQFMNKLAGRLTEPRIPASKLRGSSNRYKIKLRAAGYRLVYEVRDHELLVLVVAVGK
REHNVVDQRADQR

Download         Length: 282 bp

>T170315 NZ_CP077270:1677071-1677436 [Staphylococcus haemolyticus]
ATGATTAGAAGAGGCGATGTATATTTAGCTGATTTGTCACCAGTACAGGGCTCAGAACAAGGGGGAGTCAGACCTGTAGT
TATCATTCAAAACGATACTGGTAACAAATATAGTCCTACCGTAATCGTTGCTGCGATTACGGGAAGGATTAATAAAGCGA
AAATACCCACACATGTTGAAATCGAGAAAAAGAAATACAGACTTGATAAAGATTCAGTTATTCTACTCGAGCAAATTAGA
ACATTAGATAAAAAACGACTAAAAGAAAAATTAACATATCTATCTGATGAGAAAATGCAAGAAGTGGATGAAGCGTTAGA
CATTAGTCTAGGATTGCATGATGAAGTTAAAACGCAAAACACATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9124.41 Da        Isoelectric Point: 4.4341

>AT170315 WP_197157429.1 NZ_CP060398:c1501867-1501613 [Synechococcus sp. CBW1002]
MAHRVLTETAVSISEHKKNPMATVAAGEGMAVAVLNRNEPAFYCVPARAYEELMDLVDDLELGRIADARLTDGQEPVRVS
LDAL

Download         Length: 255 bp

>AT170315 NZ_CP077270:1676904-1677074 [Staphylococcus haemolyticus]
ATGCTTACTTTCAATCAAAATAGAAGTCACAGTCTTGAACAATCTTTAAAAGAAGGCTATGCACAAATGGCCGAATTAAA
TCTCTCCCTAGCGACAGAAGCTTTTCCTCTAGAATGCGAAGCTTGTGATTGCAACGAAACGTACCTTATTTCTAATTATA
AAAGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References