Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 2302711..2303242 Replicon chromosome
Accession NZ_CP060397
Organism Synechococcus sp. CBW1004

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag H8F25_RS10950 Protein ID WP_197210439.1
Coordinates 2302711..2302980 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag H8F25_RS10955 Protein ID WP_197210440.1
Coordinates 2302967..2303242 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8F25_RS10920 2298352..2298699 + 348 WP_197210433.1 DUF565 domain-containing protein -
H8F25_RS10925 2298707..2299744 - 1038 WP_197210434.1 aspartate carbamoyltransferase catalytic subunit -
H8F25_RS10930 2299771..2300418 - 648 WP_197210435.1 DNA-3-methyladenine glycosylase -
H8F25_RS10935 2300486..2301622 - 1137 WP_197210436.1 AAA family ATPase -
H8F25_RS10940 2301729..2302004 + 276 WP_197210437.1 BrnT family toxin -
H8F25_RS10945 2302007..2302294 + 288 WP_197210438.1 hypothetical protein -
H8F25_RS10950 2302711..2302980 - 270 WP_197210439.1 Txe/YoeB family addiction module toxin Toxin
H8F25_RS10955 2302967..2303242 - 276 WP_197210440.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
H8F25_RS10960 2303560..2304009 - 450 WP_197210441.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
H8F25_RS10965 2304503..2306725 + 2223 WP_197210442.1 methyltransferase regulatory domain-containing protein -
H8F25_RS10970 2306863..2307612 - 750 WP_197210443.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2302007..2310381 8374


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10769.41 Da        Isoelectric Point: 8.6937

>T170304 WP_197210439.1 NZ_CP060397:c2302980-2302711 [Synechococcus sp. CBW1004]
MPTAERLAWTPAAWEDYLYWQGQDRKQLRRMYQLIQACLREPFTGIGKPEPLRENLSGCWSRRIDDEHRLVYRLEASLLV
ILACRYHYR

Download         Length: 270 bp

>T170304 NZ_CP077264:3376760-3377131 [Enterobacter hormaechei]
ATGGAGCACATGGCAGTGTTTGATACCAATATTCTCATTGATCTCTTCAACAACCGTGTTGAAGCTGCGGATGCGATTGA
GCATACCGCGTCGCATCGTGCCATCAGCTTAATTACCTGGATGGAAGTAATGGTGGGCGCTCGCAGGCATGGTCATGAAG
CGAAAACGGCAGCCGTTATGGGCGCTTTTGAAATTATTGATGTGTCTCGGGATATTGCGGAAAGAAGCGTTTTACTACGT
GAGAAGCATGGAATGAAACTGCCTGATGCTATCATTCTGGCCACAGCGCAGAGCAGAAAATGTCCGTTGATTTCTCGCAA
CACGAAAGATTTTGCGGGTATTGACGAGGTCCTTACGCCTTACCAGGTGTAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10245.53 Da        Isoelectric Point: 4.8210

>AT170304 WP_197210440.1 NZ_CP060397:c2303242-2302967 [Synechococcus sp. CBW1004]
MQVVSFSEARESFKTVLDRVVADADVTLITRRHAKDAVVMSLDTYNSLMETVHLLRSPANAAHLQRSLEQAEHGELLEQP
LWEPDRADANC

Download         Length: 276 bp

>AT170304 NZ_CP077264:3376515-3376757 [Enterobacter hormaechei]
ATGAGCGTTTTGGCGGAACTTGATATGGGCAGAATACTTATCGATTTGTCTGATGACGTGATTCAACGTTTGGATAATCT
CAAGCAATTGCGAAATCAACCACGTGCTGAACTGCTTCGGGAAGCGATAGAGCTGTATCTCGACCAGCAGAGTTCTTCTG
TTATCCGAAATGCGCTTGGTCTGTGGGGAGACAGAAAAGAGGACGGGCTTGAGTATGAACGCAAGCTGCGTGAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References