Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2727933..2728600 Replicon chromosome
Accession NZ_CP060396
Organism Synechococcus sp. CBW1006

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H8F26_RS13270 Protein ID WP_197154664.1
Coordinates 2728202..2728600 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H8F26_RS13265 Protein ID WP_197154662.1
Coordinates 2727933..2728202 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8F26_RS13235 2722953..2723171 + 219 WP_197154653.1 hypothetical protein -
H8F26_RS13240 2723293..2724402 + 1110 WP_197154655.1 DUF1800 family protein -
H8F26_RS13245 2724399..2725499 + 1101 WP_197154657.1 DUF1501 domain-containing protein -
H8F26_RS13250 2725661..2726263 - 603 WP_197154658.1 DUF433 domain-containing protein -
H8F26_RS13255 2726302..2727390 - 1089 Protein_2600 IS630 family transposase -
H8F26_RS13260 2727482..2727646 - 165 WP_197154660.1 hypothetical protein -
H8F26_RS13265 2727933..2728202 + 270 WP_197154662.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
H8F26_RS13270 2728202..2728600 + 399 WP_197154664.1 type II toxin-antitoxin system VapC family toxin Toxin
H8F26_RS13275 2728900..2730060 + 1161 WP_197154665.1 ATP-binding protein -
H8F26_RS13280 2730343..2730501 - 159 WP_197154667.1 hypothetical protein -
H8F26_RS13285 2730570..2732087 + 1518 WP_197159202.1 APC family permease -
H8F26_RS13290 2732084..2733466 + 1383 WP_197154669.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(2-88)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14297.14 Da        Isoelectric Point: 4.2966

>T170294 WP_197154664.1 NZ_CP060396:2728202-2728600 [Synechococcus sp. CBW1006]
MVIDSSAVLAILQNEPERHAFNEAIAAAEQCSLSSASLVELSIVMEARFGSDGQGDLDLFLNTALIEIISLDREQAELAR
EAFSRYGKGRHRAGLNFGDCFSYALAKCLAEPLLFKGDDFCHTDLQPACPAS

Download         Length: 399 bp

>T170294 NZ_CP077262:2704876-2705052 [Citrobacter pasteurii]
GTGAAGCAAAGTGAGTTCAGACGCTGGCTTGAATCTCAGGGAGTCGCTGTTACAAACGGCTCAAATCATCTGAAACTGAG
ATATCAGGGAAGGCGTAGCGTTATGCCCAGACATCCAGGTGATGAAATAAAAGAAGCCTTGCGAAAAGCGATTATTAAGC
AGCTCGACTTACTGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9632.09 Da        Isoelectric Point: 10.9766

>AT170294 WP_197154662.1 NZ_CP060396:2727933-2728202 [Synechococcus sp. CBW1006]
VALNIRNAEASRLAAEVASLAGETKTAAVILALKERLRRLQRQSHTTANKQAALVNRLDQIALRCAGRPIGDRRSAEEIL
GYDPMGLPT

Download         Length: 270 bp

>AT170294 NZ_CP077262:2705099-2705515 [Citrobacter pasteurii]
ATGCGTTATCCCGTTACTCTAACACCGGCAGTGGAAGGTGGGTTTGTGGTTTCGTTCCCGGATATTCCGGAAGCATTAAC
TCAGGGAAATACCCGCCATGACGCTTTGCAGGCCGCGCAGGCGGCATTGATTACCGCTTTTGAATTCTATTTCGACGACA
ACGAGGCGATTCCTCTCCCCTCGGCGGTTGGCGCTGAAGATGACTACGTGGAAATACCGCTGAGCGCCGCGTCTAAGGTT
CTTTTGCTGAATGCCTTCCTTGAATCAAAAATCACCCAACAGGAACTGGCGAACAGGATCGGCAGACCTAAGCAGGAGAT
CACCCGTTTATTTGATTTAAAGCACACGACAAAAATTGATGCCGTACAGATTGCTGCGCGCGCCTTAGGCAAAGAGCTGG
CGTTAACGATGTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References