Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-relB/dnstrm_HI1420(antitoxin)
Location 886157..886858 Replicon chromosome
Accession NZ_CP060396
Organism Synechococcus sp. CBW1006

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag H8F26_RS04190 Protein ID WP_197157705.1
Coordinates 886601..886858 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H8F26_RS04185 Protein ID WP_197157703.1
Coordinates 886157..886465 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8F26_RS04155 881278..882291 - 1014 WP_197157694.1 methyltransferase -
H8F26_RS04160 882391..883299 + 909 WP_197157696.1 MBL fold metallo-hydrolase -
H8F26_RS04165 883321..884056 + 736 Protein_820 tyrosine-type recombinase/integrase -
H8F26_RS04170 885263..885472 + 210 WP_197157698.1 type II toxin-antitoxin system HicB family antitoxin -
H8F26_RS04175 885475..885702 + 228 WP_197157700.1 type II toxin-antitoxin system HicA family toxin -
H8F26_RS04180 885857..886147 + 291 WP_197157702.1 type II toxin-antitoxin system RelE/ParE family toxin -
H8F26_RS04185 886157..886465 + 309 WP_197157703.1 putative addiction module antidote protein Antitoxin
H8F26_RS04190 886601..886858 + 258 WP_197157705.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
H8F26_RS04195 886852..887187 + 336 WP_197157707.1 type II toxin-antitoxin system PemK/MazF family toxin -
H8F26_RS04200 887350..887871 + 522 Protein_827 DUF1254 domain-containing protein -
H8F26_RS04205 887955..888584 + 630 WP_197154053.1 ISAs1 family transposase -
H8F26_RS04210 888581..889120 + 540 WP_197158971.1 ISAs1 family transposase -
H8F26_RS04215 889137..890135 + 999 Protein_830 DUF1254 domain-containing protein -
H8F26_RS04220 890180..891700 + 1521 WP_197157709.1 DUF1254 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 885714..888006 2292


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Uncharacterized protein HI1420

(3-98)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9090.37 Da        Isoelectric Point: 4.3219

>T170290 WP_197157705.1 NZ_CP060396:886601-886858 [Synechococcus sp. CBW1006]
VLGVVVVRAKLVKIGNSRGIRLAKPLLEVAGLADEVEIEAAPGVLTIRPSAHPRAGWAEAASSLEPEGLLDEMSATQFDD
EEWSW

Download         Length: 258 bp

>T170290 NZ_CP077262:c1044062-1043133 [Citrobacter pasteurii]
ATGGATCTGCGTGATAGTTATGCCCGACAGGTTAGGCTATTAATGACTGCCCTGCCGCATGTGGCAAAGGAGTCCTGCTT
CGCCCTGAAAGGCGGCACGGCAATCAATTTGTTTGTACAAGATTTCCCTCGCCTGTCGGTAGATATCGATCTGGCGTATA
AGACCTATGTGGATCGCGATACCGATCTGGCTGCCATCAATGACGCCTTGATGCGTATTACTGAATCGCTGAACGGCAGA
CTGGGGATCACCGCTATCCGGCAGGAGAATAAAGCGGATGAAAAGCGCATCATCGTTAACACCGCCGATGCACAAATAAA
GATTGAGGTCAGCCCGGTGTGGCGTGGGCTACTGCTGCCATCAACAGAAATGCCGGTATGCGAACAGGTGGAAATGGAGT
ATGGCTTCACCACCATGAATGTCGTCTCGCTGGCAGACCTTTACGGCGGTAAAATCTGCGCCGCGCTCGATCGCCAGCAT
CCGCGCGATCTGTTCGACGTGCTGAATATGCTGGATAAACCGGGCCTGACGCGCGAGATTTTTGACGGTTTTCTTTGCTA
TCTGGCAGGGCATCCCCGCCCCATTGCCGAGCTGCTGGCGCCAAACTGGGATACAGCGCAGATCGCCACGCTGTACGCTC
AGGAATTTTCAGGCATGACGCAACGGGAAACGTCGCTGGAGTCGCTTCTGTCGGTAACGACCTTGCTGCCACAAGCGCTG
AAATCGCATCTTACGGAGCGGGATCGCCAGTTCTTGCTCAGTTATAAGCAAAATAACCCTGACTGGTCGCTGTATCGCTA
CCCTGAGATTCAACATCTCCCGGCTATTCGCTGGAAGTTGCGTAATCTGGCAGTGCTGAATGATAAGAATCCGGCCAAGT
ATGCGGCGGCGGTGAGCAAGTTAGAGGGGGTTCTGGCGCAGTATATTTAG

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10549.03 Da        Isoelectric Point: 4.9721

>AT170290 WP_197157703.1 NZ_CP060396:886157-886465 [Synechococcus sp. CBW1006]
MTKTITTIWDPAAHLTTADDVAAYLEAALQDGDPQLVAAALGDIARAKGMSQIAREAGLGRESLYKSLSSSGNPELATVL
KVISALGLQLHVSATDNAKMAV

Download         Length: 309 bp

>AT170290 NZ_CP077262:c1044831-1044049 [Citrobacter pasteurii]
TTGCCAAACTATATAAACTGGCTGATGCAAAACACCCAACCCGGTCAGGTGTTGCTCCAGTCATGGCTTACCCGCAACGG
CATAGATCGTAAGCTCTCTTATCTCTATGTCCAGAATGGCTGGATCAGGCGGATCGCGCACGGCGTATACTGCCGGATGG
GCCGTGAGCCGGACTGGGTGGACGCGGTTTATTGCCTGCAAACACAGTGGGAAAAGCCGGTTCGTGTGGCAGGGCTAACC
AGCCTTGCGCTACAGGGCCATGCCCACTATACCGAACCGGGCAGACAACAGATCTGGCTGGCGCTTCCGGCTTACGTCAA
ACTGCCGGGGTGGTTCGCCGCCTTTGAGCAATCCGCGAAGTTTGTCACGCTGTATACCTCTGGCCTCACCGTCGATGTGA
CACCATTCACGACAAAGCTGAATATCGGCGACCGACAGTTAACGGGCAGTATCCCGGAACTGGCCGCGTATGAGATCGCC
TGCGGCGTTCCTTCGTTGATCTCGTTCGAACATGCCGATGCCCTGTTTCAGGGAATGAACCTTCTCAGCCCGCGTAAATT
ACAAACACTGCTCTGCGCCAGTCATTCGGTTAAAACCAACCGGGTGATGCTCTATCTTGCCCGACGCAATGCGCATCCTT
ACTTTCAGTATCTCTATCAACGCGGTATAGAAACAGGCACGGGAAAGCGGCAAATCATTCCCGGCGGCTGGCTGGAGCCG
GATTATCAAATTACCGTTCCCCGCGCATTTAAACCGGAAGGAGTCGAAGATGGATCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References